seeds infected? 46 Recruiting T cells. There is evidence that cytotoxic T lym P phocytes (T cells) participate in controlling tumor growt. and that they can be harnessed to use the body's immun. system to treat cancer. One study investigated the use of T cell-engaging antibody, blinatumomab, to recruit T cell to control tumor growth. The data below are T cell counts (1000 per microliter) at baseline (beginning of the study and after 20 days on blinatumomab for six subjects in the study." The difference (after 20 days minus baseline) is the response variable. m TCELLS Baseline 0.04 0.02 O.00 0.02 0.38 0.33 After 20 days 0.28 0.47 1.30 0.25 1.22 0.44 Difference 0.24 0.45 1.30 0.23 0.84 0.11 Do the data give convincing evidence that the mean count of T cells is higher after 20 days on blinatumomah?

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please include the confidence interval and the P-value for each problem and which hypothesis to accept.and please use the calculator method not the book or excell ti 83 or 84

**Recruiting T cells**

There is evidence that cytotoxic T lymphocytes (T cells) play a role in controlling tumor growth, and they can be used to leverage the body's immune system to treat cancer. One study explored using a T cell-engaging antibody, blinatumomab, to recruit T cells in efforts to control tumor growth. The table below displays T cell counts (expressed in thousands per microliter) at the baseline (beginning of the study) and after 20 days of administering blinatumomab in six participants involved in the study. The difference calculated (after 20 days minus baseline) serves as the response variable.

|        | Subject 1 | Subject 2 | Subject 3 | Subject 4 | Subject 5 | Subject 6 |
|--------|-----------|-----------|-----------|-----------|-----------|-----------|
| Baseline         | 0.04       | 0.02       | 0.00       | 0.02       | 0.38       | 0.33       |
| After 20 days    | 0.28       | 0.47       | 1.30       | 0.25       | 1.22       | 0.44       |
| Difference       | 0.24       | 0.45       | 1.30       | 0.23       | 0.84       | 0.11       |

The study aims to determine whether these data provide convincing evidence that the average T cell count increases after 20 days of treatment with blinatumomab.
Transcribed Image Text:**Recruiting T cells** There is evidence that cytotoxic T lymphocytes (T cells) play a role in controlling tumor growth, and they can be used to leverage the body's immune system to treat cancer. One study explored using a T cell-engaging antibody, blinatumomab, to recruit T cells in efforts to control tumor growth. The table below displays T cell counts (expressed in thousands per microliter) at the baseline (beginning of the study) and after 20 days of administering blinatumomab in six participants involved in the study. The difference calculated (after 20 days minus baseline) serves as the response variable. | | Subject 1 | Subject 2 | Subject 3 | Subject 4 | Subject 5 | Subject 6 | |--------|-----------|-----------|-----------|-----------|-----------|-----------| | Baseline | 0.04 | 0.02 | 0.00 | 0.02 | 0.38 | 0.33 | | After 20 days | 0.28 | 0.47 | 1.30 | 0.25 | 1.22 | 0.44 | | Difference | 0.24 | 0.45 | 1.30 | 0.23 | 0.84 | 0.11 | The study aims to determine whether these data provide convincing evidence that the average T cell count increases after 20 days of treatment with blinatumomab.
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