Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Question
See attached image
![7) a. Below is a Lasonolide A, a natural product with high cytotoxicity against a number of cancers. Assign the
stereochemical configuration of the selected tetrahedral carbon chiral centers (R, S or N (not a chiral center))
and the alkene (E, Z or N (not a stereocenter)) that are indicated by the arrows (note that you do not have to
assign the configuration of every chiral center in the molecule). If the atom in question is not a chiral center or
is not a stereocenter circle N for neither.
R
S
N
N
1
OH
N
E
11
E
N
1
HO
E
N Z
R
S
N
OH
R
N
R
N
Lasonolide A
b. Circle the functional groups that are present in the Lasonolide A.
amine
alcohol
ether
aldehyde
ketone
ester
amide
carboxylic acid,](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F611625c6-9dd6-4a84-b59d-ca7aa1a3b1b7%2Faef72dc0-8cc9-446d-b4e0-7caea3eb6ed1%2Fymw1xkr_processed.png&w=3840&q=75)
Transcribed Image Text:7) a. Below is a Lasonolide A, a natural product with high cytotoxicity against a number of cancers. Assign the
stereochemical configuration of the selected tetrahedral carbon chiral centers (R, S or N (not a chiral center))
and the alkene (E, Z or N (not a stereocenter)) that are indicated by the arrows (note that you do not have to
assign the configuration of every chiral center in the molecule). If the atom in question is not a chiral center or
is not a stereocenter circle N for neither.
R
S
N
N
1
OH
N
E
11
E
N
1
HO
E
N Z
R
S
N
OH
R
N
R
N
Lasonolide A
b. Circle the functional groups that are present in the Lasonolide A.
amine
alcohol
ether
aldehyde
ketone
ester
amide
carboxylic acid,
Expert Solution
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Step 1
Number the four groups attached to the central carbon atom. Higher the atomic number more would be the priority of that group.If the numbering goes in the clockwise direction then the configuration would be R configuration and vice versa.
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