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- 23 Which statement describes a disease state caused by altered protein structure? A silent mutation in hyaluronidase disnupts mucosal function OA slent mutation in arachidonic acid disrupts eicosanoid production O A missense mutation in heokinase disrupts glycolysis OA ronsense mation in ATP disrupts energy metabolsmExplain how glucose is metabolized to yield ATP.Explain why some dietary lipid is a necessary part of a balanced diet.
- Ketone bodies are used as an alternative source of fuel during starvation. Describe how ketones are synthesized.2a. Describe the structural differences between cellulose and glycogen. 2b. State one structural feature of glycogen accounting for its energy storage role.List the ketone bodies. Where are they synthesized and where are they used?
- Answer the ff. questions: 1. To which class does each enzyme belong? Explain your answers. a.) pyruvate decarboxylase b.) alanine aminotransferase c.) alcohol dehydrogenase d.) hexokinase 2. Substrates and reactive groups in an enzyme’s active site must be precisely aligned in order for a productive reaction to occur. Why, then, is some conformational flexibility also a requirement for catalysis? 3. Some plants contain compounds that inhibit serine proteases. It has been hypothesized that these compounds protect the plant from proteolytic enzymes of insects and microorganisms that would damage the plant. Tofu, or bean curd, possesses these compounds. Manufacturers of tofu treat it to eliminate serine protease inhibitors. Why is this treatment necessary?Q.33. Calculate the number of ATP molecules obtained from the anaerobic conversion of each of the following sugars to lactate Show the equation. a. Mannose b. SucroseH8. Glucose labeled with 14 C at C-1 is added to a solution containing the enzymes and cofactors of the oxidative phase of the pentose phosphate pathway (aka hexose monophosphate pathway) which compounds will contain radioactive carbon? - Ribulose 5 phosphate, no label will be found, all compounds will be labeled, erythrose 4- phosphate, 7-[hps[hpsedoheptulose, fructose 6- phosphate, grlyceraldehyde 3-phosphate, xylulose 5 phosphate ribose 5 phosphate
- IDENTIFICATION 1. A type of reaction that occurs when an energy absorbing reaction requires an input from an energy releasing reaction. 2. What does ATP stands for? 3. What does ADP stands for? 4. When a phosphate bond is broken energy is released from ATP. This type of reaction is 5. To reconnect the phosphate with ADP energy must be absorbed from the breakdown of glucose during cellular metabolism. This type of reaction that occurs with glucose is 6. A biochemical process that involves the addition of phosphate to an organic compound. 7. How many kilojoules is released with ADP is reduced to ADP? 8. ATP is also formed from the process of cellular respiration in the mitochondria of a cell through 9. ATP is also produced in bacteria in the absence of oxygen called 10. A method in food processing which can produce small amounts of ATP is called8. In patients with diabetes mellitus type 1, the biochemical disorders result from changes in fuel metabolism. One of these signs is acidosis, Explain why such patients have a deviation of blood pH from the norm? For this 9. b) write the reactions of synthesis and oxidation of these molecules, name the enzymes, coenzymes, reaction localization: Xi.What is mutarotation? What is the consequence of mutarotation? ii. Explain why lactose and maltose can be direct reactants in the Maillard reaction while sucrose cannot be.
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