Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter4: Chemical Reactions
Section: Chapter Questions
Problem 4.100P
Related questions
Question
Amide B hydrolyzes about 100,000 times faster than amide A (k 2 >>k1 ) even tho in same conditions. Please explain why b is faster using resononace structures and if they occur in tetrahedral mechanism .
![R₁
NaOH, H₂O
'N'
K₁
R₁
A
ANH
NH-O
B
NaOH, H₂O
K2
R₁
CNH + O](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fe6590fdc-f2c3-4a7f-8946-b9d91889ea7c%2F0473510d-3a9f-467c-ab12-4b78210d86f8%2Fqbin68n_processed.png&w=3840&q=75)
Transcribed Image Text:R₁
NaOH, H₂O
'N'
K₁
R₁
A
ANH
NH-O
B
NaOH, H₂O
K2
R₁
CNH + O
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