Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter4: Chemical Reactions
Section: Chapter Questions
Problem 4.100P
Related questions
Question
Amide B hydrolyzes about 100,000 times faster than amide A (k 2 >>k1 ) even tho in same conditions. Please explain why b is faster using resononace structures and if they occur in tetrahedral mechanism .

Transcribed Image Text:R₁
NaOH, H₂O
'N'
K₁
R₁
A
ANH
NH-O
B
NaOH, H₂O
K2
R₁
CNH + O
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