Question 4. Recalling the eye pigment pathway in Drosophila, match the following fly genotypes with the appropriate phenotypes (w=white, bw-brown, cn=cinnabar red, st=scarlet red, se-sepia brown) a. b. C. d. W W W W + ; ; ; ; bw + bw + + cn bw + Genotype A + cn bw cn bw cn Genotype B Genotype C + cn Genotype D ; ; ; ; st+ st se st se + se st se + se st se + se Scarlet Sepia Sepia White < < > <
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- Explain about how X chromosome inactivation takes place in mammals at the chromosomal and molecular level. B. What genes are involved in inactivating a human X chromosome? . C. What role does X chromosome-specific inactivating transcript --XIST-- non coding RNA play in the inactivation of the human X chromosome.How three-point crosses verify Sturtevant’s map of the Drosophila X chromosome.Question:- A female fruit fly that is heterozygous for the white-eye mutation has red-eyed sons and white-eyed sons in equal proportions: a. regardless of the genotype of the male. b. only when mated with a red-eyed male. c. only when mated with a white-eyed male. d. only when mated with a heterozygous male.
- List and describe 4 of the main regulators of the cell cycle. Then describe the involvement of a CDK substrate at each stage of the cell cycle: G1, S, G2, M. 2. DESCRIBE (do not just list) three mechanisms that keep the cell cycle moving in only one direction. Then describe how these mechanisms play a role at one specific stage of the cell cycle. 3. What are the three main classes of genes implicated in cancer? Describe each one and give an example of each one. 4. DESCRIBE (do not just list) 4 developmental strategies that cause different cells and tissues to acquire different identities during embryogenesis. Then explain how iPS cells are an exception to the overall trend of cells decreasing in pluripotency as they develop. 5. Describe three unique cell biological features of sperm cells and three unique cell biological features of egg cells. By "unique", I mean a feature that is not common in most cells. 6. You have just identified a mouse gene that is homologous to other vertebrate…Recall that the nuclear membrane disintegrates late in prophase of mitosis in most eukarvotic cells. Once the membrane is reformed in telophase in a daughter cell, several components of gene expression mignt therefore be "caught" out in the cytoplasm when they would otherwise onlv ever be found inside the nucleus. Consider where the following components of gene expression are made and where they runction. Which component is normally never found in the cytoplasm outside the nucleus? O A. Spliced intron • B. RNA polymerase O C. Histones • D. DNA polymerase* b. Briefly explain how the use of this molecule (CA1P) disrupts both stages of photosynthesis while the Rubisco enzyme is associated with only one stage. Codule 3: The principles of heredity 1. Let's take the example of the gray kangaroo (Macropus fuliginosus) whose ploidy is 8 and the sexual determinism of this species is carried out according to the XY mode. From a male kangaroo: a) Draw the karyotype of this individual, obtained by stopping division at metaphase. Your drawing should include: a. All maternal and paternal chromosomes involved (different colors) b. An example of autosome and heterochromosome c. An example of homologous chromosome, sister chromatid and centromere. d. The total number of chromosomes in a metaphase kangaroo cell. e. A sentence to explain the difference between the terms gene and allele that might apply to this species. Page 3/4 Sh Q + 9 CA 9 0 11:57 M DELL