Question 4 5/ 6 points Marybeth uses a library of venomous toxins to test their influence on neuronal firing. Below is a a summary of the effects. Predict what type of change would occur to neuronal activity. You can put I for increase or D for decrease. Toxin 1 2 3 4 5 6 Drug Effect Blocks Voltage-gated Na+ channels Decreases the sensitivity of the voltage sensing component of a Na+ channel so it requires more of a positive potential. Increases the period of hyperpolarization Causes the Na+/K+ pump to be more effective at moving K+ into the cell resulting in reduced K+ extracellular levels. Causes the concentration gradient of Cl- to flip so that when Cl- channel open you get? Blocks passive leak channels for K+. Reducing the relative perameability of K+ at rest. Neuronal activity (increased or decreased)

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Question 4
5/ 6 points
Marybeth uses a library of venomous toxins to test their influence on neuronal firing. Below is a a summary
of the effects. Predict what type of change would occur to neuronal activity. You can put I for increase or D
for decrease.
Toxin
1
2
3
4
5
6
Drug Effect
Blocks Voltage-gated Na+ channels
Decreases the sensitivity of the voltage
sensing component of a Na+ channel so
it requires more of a positive potential.
Increases the period of
hyperpolarization
Causes the Na+/K+ pump to be more
effective at moving K+ into the cell
resulting in reduced K+ extracellular
levels.
Causes the concentration gradient of Cl-
to flip so that when Cl- channel open
you get?
Blocks passive leak channels for K+.
Reducing the relative perameability of
K+ at rest.
Neuronal activity
(increased or decreased)
Transcribed Image Text:Question 4 5/ 6 points Marybeth uses a library of venomous toxins to test their influence on neuronal firing. Below is a a summary of the effects. Predict what type of change would occur to neuronal activity. You can put I for increase or D for decrease. Toxin 1 2 3 4 5 6 Drug Effect Blocks Voltage-gated Na+ channels Decreases the sensitivity of the voltage sensing component of a Na+ channel so it requires more of a positive potential. Increases the period of hyperpolarization Causes the Na+/K+ pump to be more effective at moving K+ into the cell resulting in reduced K+ extracellular levels. Causes the concentration gradient of Cl- to flip so that when Cl- channel open you get? Blocks passive leak channels for K+. Reducing the relative perameability of K+ at rest. Neuronal activity (increased or decreased)
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