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QUESTION 11 A child presents a clinical indication of chronic pneumonia, low weight, persistent cough and thick mucus associated with cystic fibrosis (CF). Their older sibling has recurring sinusitis but their younger sibling and both parents are asymptomatic. Genetic testing reveals everyone in the family has several mutations on chromosome 7 where the CFTR gene is located. What explains the differences in phenotype severity observed in this family? The CFTR gene is pleiotrophic, and disease severity is determined by the recessive alleles inherited The CFTR gene is an example of incomplete dominance CF is a polygenic inherited disease, and disease severity is determined by the recessive alleles inherited CF is a polygenic inherited disease, and disease severity is determined by the dominant alleles inherited The CFTR gene is pleiotrophic, and disease severity is determined by the dominant alleles inherited

QUESTION 11 A child presents a clinical indication of chronic pneumonia, low weight, persistent cough and thick mucus associated with cystic fibrosis (CF). Their older sibling has recurring sinusitis but their younger sibling and both parents are asymptomatic. Genetic testing reveals everyone in the family has several mutations on chromosome 7 where the CFTR gene is located. What explains the differences in phenotype severity observed in this family? The CFTR gene is pleiotrophic, and disease severity is determined by the recessive alleles inherited The CFTR gene is an example of incomplete dominance CF is a polygenic inherited disease, and disease severity is determined by the recessive alleles inherited CF is a polygenic inherited disease, and disease severity is determined by the dominant alleles inherited The CFTR gene is pleiotrophic, and disease severity is determined by the dominant alleles inherited

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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QUESTION 11 A child presents a clinical indication of chronic pneumonia, low weight, persistent cough and thick mucus associated with cystic fibrosis (CF). Their older sibling has recurring sinusitis but their younger sibling and both parents are asymptomatic. Genetic testing reveals everyone in the family has several mutations on chromosome 7 where the CFTR gene is located. What explains the differences in phenotype severity observed in this family? The CFTR gene is pleiotrophic, and disease severity is determined by the recessive alleles inherited The CFTR gene is an example of incomplete dominance CF is a polygenic inherited disease, and disease severity is determined by the recessive alleles inherited CF is a polygenic inherited disease, and disease severity is determined by the dominant alleles inherited The CFTR gene is pleiotrophic, and disease severity is determined by the dominant alleles inherited
Transcribed Image Text:QUESTION 11 A child presents a clinical indication of chronic pneumonia, low weight, persistent cough and thick mucus associated with cystic fibrosis (CF). Their older sibling has recurring sinusitis but their younger sibling and both parents are asymptomatic. Genetic testing reveals everyone in the family has several mutations on chromosome 7 where the CFTR gene is located. What explains the differences in phenotype severity observed in this family? The CFTR gene is pleiotrophic, and disease severity is determined by the recessive alleles inherited The CFTR gene is an example of incomplete dominance CF is a polygenic inherited disease, and disease severity is determined by the recessive alleles inherited CF is a polygenic inherited disease, and disease severity is determined by the dominant alleles inherited The CFTR gene is pleiotrophic, and disease severity is determined by the dominant alleles inherited
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