Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity ofPP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA).[MBP](mg-mL-¹)0.0100.0150.0250.050Vo without PA(nmol-mL-¹ min-¹)0.02090.03550.04190.0838Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid?UncompetitiveNoncompetitiveMixed inhibitionCompetitiveVo with PA(nmol-mL-¹ min-¹)0.003810.006200.009310.01400

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Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity of PP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA). [MBP] (mg-mL-1) 0.010 0.015 0.025 0.050 Vo without PA (nmol-mL-¹ min-¹) Uncompetitive Noncompetitive Mixed inhibition Competitive 0.0209 0.0355 0.0419 0.0838 Vo with PA (nmol-ml-1.min-¹) 0.00381 Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid? 0.00620 0.00931 0.01400

Protein phosphatase 1 (PP1) helps regulate cell division and is a possible drug target to treat certain types of cancer. The enzyme catalyzes the hydrolysis of a phosphate group from myelin basic protein (MBP). The activity of PP1 was measured in the presence and absence of the inhibitor phosphatidic acid (PA). [MBP] (mg-mL-1) 0.010 0.015 0.025 0.050 Vo without PA (nmol-mL-¹ min-¹) Uncompetitive Noncompetitive Mixed inhibition Competitive 0.0209 0.0355 0.0419 0.0838 Vo with PA (nmol-ml-1.min-¹) 0.00381 Use the data in the table to construct a Lineweaver-Burk plot. What type of inhibitor is phosphatidic acid? 0.00620 0.00931 0.01400

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Question 14 of 58 Click to see additional instructions The rate of an enzyme-catalyzed reaction (in mM/min) was determined at different concentrations of substrate On a double-reciprocal Ginewnaver-Burk) plot of the data, the intercept wi -0.01 mM and the slope was 0.05 min. Determine the two values below and give your answer as a whole number (no decimals). Acceptable Characters Only numbers, decimal point markers, or sign indicators preceding a number Vmax mM/min Km mM
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