Predict only the FINAL product (or a mixture of products) for the following synthetic transformation: H3CO A NH Br2 AlBr3 O₂N NO2 B D A. H3CO (2 moles) HNO3 H2SO4 NH2 Chemical Formula: C6H3BгN2O4 O₂N. NO2 OCH 3 ? H3CO. H₂N. NH NO2 O₂N NO2 NO2 NO2 B. C. D.
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- Which of the following structures and IUPAC names are incorrectly matched? * oe (A) Methyleyclohexanoate (В) `NH2 Br 4-Bromo-3-chlorohexanamide 2-Ethoxypentane (D) HOOC HOOC 3,5-Nonanedioic acid В A DH3C OH 1. Br2, PBг3 2. H₂O H3C OH Br The a-bromination of carbonyl compounds by Br₂ in acetic acid is limited to aldehydes and ketones because acids, esters, and amides don't enolize to a sufficient extent. Carboxylic acids, however, can be a-brominated by first converting the carboxylic acid to an acid bromide by treatment with PBr3. Following enolization of the acid bromide, Br2 reacts in an a-substitution reaction. Hydrolysis of the acid bromide completes the reaction. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions Br Br зь P-Br Br H₂C H₂C SH Br BrWhat is the major organic product of the following reaction? HO CI 1. CH3CH2MgBr برام (2 equiv) 2. H₂O HO CI CICI EU Multiple Choice TV of IV
- Identify A, B, and C, intermediates in the synthesis of the five-membered ring called an α- methylene-γ-butyrolactone. This heterocyclic ring system is present in some antitumor agents.Which is the major product from the acid catalyzed hydrolysis of cyclohexene oxide? но OH но он || II IVRank the reactivity of the compounds below toward nucleophilic acyl substitution by writing the compounds' letters in the proper blanks in the box below. `NH CI Br CH3 CH3 A В C E rank compounds for acyl substitution reactivity most least reactive reactive
- The following diol is prepared from propanal (CH3CH2CHO) and 3-bromopropanol. Which derivatives will be among intermediate products in this transformation? ОН HOWhat is the major organic product obtained from the following reaction? H HC A) 1 B) 2 HO H₂SO4 C) 3 OH 2 سل، ز. مل D) 4 OHProvide reagents/conditions to accomplish the following syntheses. Several steps are required in some cases. H2N NH2 Но TH. NH2 HO
- Complete the following reaction sequence with the missing major organic products. CH, NaOH CH,CH,CH,CHCH,CHCH,CEN H20 NaOH H,0 CH,CH,Which one of the following carboxylic acid derivatives can undergo nucleophilic acyl substitution without the need of an acid to catalyze the reaction? O CH3C=N ОН `NH2#16d. Provide the missing reactants, reagents, or products for the following reaction sequences below.