Please order the steps of myofilament movement. Myosin heads are "energized" by the presence of ADP + PO43-at the ATP binding site (energy is released as phosphate bond of ATP breaks). Once the active sites are exposed, the energized myosin heads hook into actin molecules forming cross-bridges = A new molecule of ATP binds to the myosin head, causing the cross bridge to detach from the actin strand. The myosin head will get re-energized. = The myosin head can bind again to the next active site. Using the stored energy, the attached myosin heads pivot toward the center of the sarcomere. The ADP & phosphate group are released from the myosin head Calcium (Ca+2) gates in the SR open, allowing Ca+2 to diffuse into the sarcoplasm. Calcium will bind to troponin (on the thin myofilament), causing it to change its shape. This then pulls tropomyosin away from the active sites of actin molecules. 12 13 14 15 16 17 18 19 20 21

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter8: Muscle Physiology
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Please order the steps of myofilament movement.
Please order the steps of myofilament movement.
Myosin heads are "energized" by the presence of ADP + PO43-at the ATP binding site (energy is released as phosphate bond of ATP breaks). Once
the active sites are exposed, the energized myosin heads hook into actin molecules forming cross-bridges
= A new molecule of ATP binds to the myosin head, causing the cross bridge to detach from the actin strand. The myosin head will get re-energized.
= The myosin head can bind again to the next active site.
Using the stored energy, the attached myosin heads pivot toward the center of the sarcomere. The ADP & phosphate group are released from the
myosin head.
Calcium (Ca+2) gates in the SR open, allowing Ca+2 to diffuse into the sarcoplasm. Calcium will bind to troponin (on the thin myofilament), causing
it to change its shape. This then pulls tropomyosin away from the active sites of actin molecules.
12 13 14 15 16 17 18 19 20 21
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Transcribed Image Text:Please order the steps of myofilament movement. Myosin heads are "energized" by the presence of ADP + PO43-at the ATP binding site (energy is released as phosphate bond of ATP breaks). Once the active sites are exposed, the energized myosin heads hook into actin molecules forming cross-bridges = A new molecule of ATP binds to the myosin head, causing the cross bridge to detach from the actin strand. The myosin head will get re-energized. = The myosin head can bind again to the next active site. Using the stored energy, the attached myosin heads pivot toward the center of the sarcomere. The ADP & phosphate group are released from the myosin head. Calcium (Ca+2) gates in the SR open, allowing Ca+2 to diffuse into the sarcoplasm. Calcium will bind to troponin (on the thin myofilament), causing it to change its shape. This then pulls tropomyosin away from the active sites of actin molecules. 12 13 14 15 16 17 18 19 20 21 Support | Schoology Blog | PRIVACY POLICY | Terms of Use VIZIO 1080P FULL HO SJS
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The acting is a component of cytoskeleton protein. It is responsible for muscle contraction together with the help of actin binding protein known as myosin. Myosin is a motor protein that can binds and hydrolyzed ATP.

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