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Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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LABORATORY EXERCISES IN GENETICS
Name
Laboratory Instructor
CourselYear/Soc
Date
Activity Sheet
MENDELIAN MODE OF INHERITANCE AND PEDIGREE ANALYSIS
Dent disease is a rare disorder of the kidney in which there is impaired
reabsorption of fitered solutes and progressive renal failure. The following
pedigree shows the pattern of inheritance for this disorder.
1.
a. On the basis of this pedigree, what is the most likely mode of inheritance for the
disease?
b. From your answer to part a, give the most likely genotypes for the following
persons in the pedigree:
|-1:
1-2:
II-5:
Il-8:
III-1:
III-3:
IV-2:
IV-1:
2.
The foliowing pedigree illustrates the inheritance of Duchenne Muscular
Dystrophy, a condition characterized by progressive weakness and degeneration
of skeletal muscles due to absence of dystrophin.
58
Transcribed Image Text:LABORATORY EXERCISES IN GENETICS Name Laboratory Instructor CourselYear/Soc Date Activity Sheet MENDELIAN MODE OF INHERITANCE AND PEDIGREE ANALYSIS Dent disease is a rare disorder of the kidney in which there is impaired reabsorption of fitered solutes and progressive renal failure. The following pedigree shows the pattern of inheritance for this disorder. 1. a. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? b. From your answer to part a, give the most likely genotypes for the following persons in the pedigree: |-1: 1-2: II-5: Il-8: III-1: III-3: IV-2: IV-1: 2. The foliowing pedigree illustrates the inheritance of Duchenne Muscular Dystrophy, a condition characterized by progressive weakness and degeneration of skeletal muscles due to absence of dystrophin. 58
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