Please answer subquestions 1.a and 1.b Question 1.a: A mutation in MAPK makes it constitutively active. If cells are treated with the control treatment (no EGF) will be observed. When cells are treated with EGF will be observed. A. No proliferation; proliferation B. Proliferation; proliferation C. No proliferation; no proliferation D. Proliferation; no proliferation Question 1.b: In order to prevent a specific event (step), from occurring in a pathway (e.g, the phosphorylation of MAPKK), you should target the portion of the cascade with an inhibitor. A. Downstream B. Extracellular C. Nuclear D. Upstream
Please answer subquestions 1.a and 1.b
Question 1.a:
A mutation in MAPK makes it constitutively active. If cells are treated with the control treatment (no EGF) will be observed. When cells are treated with EGF will be observed.
A. No proliferation; proliferation
B. Proliferation; proliferation
C. No proliferation; no proliferation
D. Proliferation; no proliferation
Question 1.b:
In order to prevent a specific event (step), from occurring in a pathway (e.g, the phosphorylation of MAPKK), you should target the portion of the cascade with an inhibitor.
A. Downstream
B. Extracellular
C. Nuclear
D. Upstream
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