PJA01 Based on your knowledge of local anesthetic SAR, which of the following drugs will block the sodium channel by binding to the hydrophobic site? See attachment. N OC4H9 come Drug A C4H9HN Drug B O Drug C Drug A O Drug D Drug C H₂N CH3 CH3 Drug B -C₂H5 CH3 NH CH3 Drug D N CH3
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- Pls help, sorry for the trouble Explain what the exocytosis of the neurotransmitter does.Explain the experimental procedure used byLoewenstein to determine the size of molecules that can passthrough gap-junction channels.Please ASAP. Thank you. Hyperpolarization activated cyclic nucleotide modulated channels (HCN). How is this channel activated? What is predominant ion that flows through this channel?
- The tight binding sites required for ion selectivity should slow the progress of ions through a channel, yet ion channels achieve rapid rates of ion transport. How is this paradox resolved?(1) Discuss the structure and function of ion channels and describe their importance in medicinal chemistry. (ii) Draw the molecular structure of tamoxifen and discuss, in detail, its mode of therapeutic activity. Use the protein databank (PDB entry: 3ERT) to help support your answer.5.Myasthenia (muscle weakness)is characterized by damage in the transmission of neurotic impuise and decreased amount of acetylcholine due to autoimmune mechanisms. Prozerine is used for treatment of this disease.Specify the mechanism of this drug action. For this: 1)Write the reaction of acetylcholine degradation at neuromuscular junction. 2)What enzyme will be inhibited with prozerine? Name the class of this enzyme. 3)What is the mechanism of this enzyme inhibition?
- Show where trypsin and chymotrypsin would cleave the following peptide Tyr-Ile-Gin-Arg-Leu-Gly-Phe-Lys-Asn-Trp-Phe-Gly-Ala-Lys-Gly-Gin Ginthe game. And the game officially started! The game will work by team. Sakuragi and his team are placed in small submarine shrunk down to microscopic size and injected into a stained living ceili. The teams goai is to find out what is happening in the area because the object is slowly occupying the space where there are many creatures are living. They started their path on the fluid. As they continue their journey, they reached in a transparent layer. In order to make the navigational adjustment, 1. they need to identify this substance. What could be this thing? They scanned the area using an ultra telescope designed by the company that useful for their goal. Upon using the tool they have found out that it contains a wide variety of biological molecules magnification micro 2 There are polar and non - polar region. What are these biomolecules? They tried to get insideVasopressin: CYFQNCPRG Oxytocin: CYIQNCPLG Both of these peptides will react with reducing agents such as beta mercaptoethnol (BME). What side group reacts with this reducing agent? What does the fact that these peptides both react with BME tell you about the side groups and therefore this peptide?
- Define channel proteinpQLScB3CBS-8U2yQp5UAPJA-R3spS6YB8srqTGBoSwdXc_EattnA/viewform dvisor Main... My Drive - Google... Your answer What is the difference between primary active transport and secondary active transport? The sodium potassium pump * Job Listing - USF... WT Enrollment Requir... Is a symporter Can be blocked with drugs Controls intracellular chloride and potassium concentrations Is a glycolipid Breaks down ATP in order to generate energy ATP can be broken down to generate energy * True False A copy of your responses will be emailed to lc21-0506@lclark.edu. Submit Chemic CleExplain why this is not true about ion channel receptors; It forms hydrophobic hollow because it is a membrane bound receptor.