Peptide 1: VALKTQAM Peptide 2: LDGKM Peptide 3: TQAM Peptide 4: LDGK Peptide 5: MVALK The sequence of the original peptide is:

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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4- You have isolated a peptide, which you wish to sequence. First you treat the
peptide with CNBr and isolate two fragments. In a separate test of the peptide you
cleave with trypsin and obtain 3 fragments. You sequence each of the five peptides
and get the following data:
Peptide 1: VALKTQAM
Peptide 2: LDGKM
Peptide 3: TQAM
Peptide 4: LDGK
Peptide 5: MVALK
The sequence of the original peptide is:
Transcribed Image Text:4- You have isolated a peptide, which you wish to sequence. First you treat the peptide with CNBr and isolate two fragments. In a separate test of the peptide you cleave with trypsin and obtain 3 fragments. You sequence each of the five peptides and get the following data: Peptide 1: VALKTQAM Peptide 2: LDGKM Peptide 3: TQAM Peptide 4: LDGK Peptide 5: MVALK The sequence of the original peptide is:
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