Patients with acromegaly have increased circulating levels of GH and exhibit abnormal glucose tolerance due to severe insulin resistance. Explain why growth hormone is diabetogenic.
Patients with acromegaly have increased circulating levels of GH and exhibit abnormal glucose tolerance due to severe insulin resistance. Explain why growth hormone is diabetogenic.
Hormonal disorders are generally caused by either low-level release (hyposecretion) or high-level release( hypersecretion). Hormonal disorders can be caused by defects in hormone receptors, and defects in secondary messengers.
Growth Hormones are secreted from the hypothalamus. Growth hormone-releasing hormone (GHRH) is also known as the growth hormone-releasing factor. Growth hormone promotes the movement of amino acids into cells and the incorporation of these amino acids into proteins. It promotes organ development. Somatostatin hormone inhibits the growth-releasing hormone.
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