past 20 years. About 1 week ago, he noticed a sudden onset of shaking chills, fever, sweating, malaise, chest pain, and shortness of breath at rest. He also began coughing up rust-colored sputum that was thicker than his normal sputum production. Mt. C admits to current consumption of two packs per day of cigarettes (ie 70 pack-year smoking history). He admits to occasional alcohol use but denies having orthopnea, ankle edema, nausea, vomiting, diarrhea, weight loss, dysuria, wheezing, or hemoptysis. His paO2 = 44 mmHg (small paO2) Mr. C's arterial blood gas analysis indicates respiratory alkalosis with hypoxemia.  Part 1: His PAO2 is approximately 109.73 mmHg  Part 2: His A-a gradient is 65.73 mmHg Part 3: HIs dead space to tidal volume (vd/vt) is equal to 0.52 Please explain what is clinically happening to the patient?

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Case #3 Mr. C is a 60-year-old male who lives in his 1994 Toyota Corolla. He earns money by collecting aluminum cans along the roadside and from trash dumpsters. He states that he has been coughing up about ¼ cup of white sputum each morning for the past 20 years. About 1 week ago, he noticed a sudden onset of shaking chills, fever, sweating, malaise, chest pain, and shortness of breath at rest. He also began coughing up rust-colored sputum that was thicker than his normal sputum production. Mt. C admits to current consumption of two packs per day of cigarettes (ie 70 pack-year smoking history). He admits to
occasional alcohol use but denies having orthopnea, ankle edema, nausea, vomiting, diarrhea, weight loss, dysuria, wheezing, or hemoptysis. His paO2 = 44 mmHg (small paO2)

Mr. C's arterial blood gas analysis indicates respiratory alkalosis with hypoxemia. 

Part 1: His PAO2 is approximately 109.73 mmHg 

Part 2: His A-a gradient is 65.73 mmHg

Part 3: HIs dead space to tidal volume (vd/vt) is equal to 0.52

Please explain what is clinically happening to the patient?

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