What is the likely diagnosis, based on history and tests noted above? Justify your answer briefly. 2. What is the likely significance of the elevated serum calcium, and how might it be related to the abnormal findings in the lung?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Read the case description carefully and then respond to the individual questions.

Primary complaints/recent history of illness

  • 60-year-old male comes into his family physician with complaint of persistent hoarseness for past three weeks that interferes with conversation.
  • Reports usual "smoker's cough" has worsened in past few months.

Other history (past, family, social), allergies, medications

  • Cigarette smoking, 1-2 packs per day since teenage years
  • Intermittent hemoptysis for one year--not reported in previous physician visits
  • Iron-deficiency anemia for past six months--same physician prescribed ferrous sulfate (325 mg/day, oral)
  • Social drinker, 1-2 drinks per day reported
  • Mild seasonal allergies since teenage years

Physical exam

  • Height, 5'10"; weight, 195 lb.
  • Auscultation: wheezing localized in upper right lobe on inspiration
  • Percussion: resonance/dullness over upper right lobe
  • BP: 120/75 mm Hg; 
  • pulse: 90, regular; respiration 25, slightly labored
  • temperature: 98.9 F
  • Other exam results unremarkable

Diagnostic tests

  • Chest X-ray at right:
  • Pulmonary function tests: FEV1 1.9 liters, FVC 2.9 liters
  • Serum electrolytes all within normal range, except calcium, which is 3.0 mmol/liter (6 mEq/liter; 11.4 mg/dL)

1. What is the likely diagnosis, based on history and tests noted above? Justify your answer briefly.

2. What is the likely significance of the elevated serum calcium, and how might it be related to the abnormal findings in the lung?

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