P 35. Alpha substitution reactions occur at the position next to the carbonyl group, the a- position. This position is acidic and a strong base can abstract the a-proton forming an enolate anion. This enolate can act as a strong nucleophile to be used in a number of different reactions. Step 2 of the scheme below shows the enolate involved in nucleophilic addition with benzaldehyde. Provide the full mechanism (curved arrows and Intermediates) of the nucleophilic addition reaction that occurs in step 2. H base enolate 1) benzaldehyde 2) H₂O+ OH Ph

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35. Alpha substitution reactions occur at the position next to the carbonyl group, the a-
position. This position is acidic and a strong base can abstract the a-proton forming an
enolate anion. This enolate can act as a strong nucleophile to be used in a number of
different reactions. Step 2 of the scheme below shows the enolate involved in
nucleophilic addition with benzaldehyde. Provide the full mechanism (curved arrows and
Intermediates) of the nucleophilic addition reaction that occurs in step 2.
base
enolate
1) benzaldehyde
2) H₂O+
OH
Ph
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Transcribed Image Text:er 35. Alpha substitution reactions occur at the position next to the carbonyl group, the a- position. This position is acidic and a strong base can abstract the a-proton forming an enolate anion. This enolate can act as a strong nucleophile to be used in a number of different reactions. Step 2 of the scheme below shows the enolate involved in nucleophilic addition with benzaldehyde. Provide the full mechanism (curved arrows and Intermediates) of the nucleophilic addition reaction that occurs in step 2. base enolate 1) benzaldehyde 2) H₂O+ OH Ph Send a chat
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