Organizers in animal embryos (a) Transplant (b) Transplant of ZPA Extra digits with reverse polarity ZPA- FIGURE 13-2 Transplantation experiments played a central role in early embryology and demonstrated the long-range organizing activity of embryonic tissues. (a) The Spemann organizer. The dorsal blastopore "lip" of an early amphibian embryo can induce a second embryonic axis and embryo when transplanted to the ventral region of a recipient embryo. (b) In the developing chick vertebral limb bud, the zone of polarizing activity (ZPA) organizes pattern along the anteroposterior axis. Transplantation of the ZPA from a posterior to anterior position induces extra digits with reverse polarity.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In Figure 13-2, the transplantation of certain regions of
embryonic tissue induces the development of structures
in new places. What are these special regions called, and
what are the substances they are proposed to produce?

Organizers in animal embryos
(a)
Transplant
(b)
Transplant
of ZPA
Extra digits with
reverse polarity
ZPA-
FIGURE 13-2 Transplantation experiments played a central role in early embryology and
demonstrated the long-range organizing activity of embryonic tissues. (a) The Spemann
organizer. The dorsal blastopore "lip" of an early amphibian embryo can induce a second
embryonic axis and embryo when transplanted to the ventral region of a recipient embryo.
(b) In the developing chick vertebral limb bud, the zone of polarizing activity (ZPA) organizes
pattern along the anteroposterior axis. Transplantation of the ZPA from a posterior to
anterior position induces extra digits with reverse polarity.
Transcribed Image Text:Organizers in animal embryos (a) Transplant (b) Transplant of ZPA Extra digits with reverse polarity ZPA- FIGURE 13-2 Transplantation experiments played a central role in early embryology and demonstrated the long-range organizing activity of embryonic tissues. (a) The Spemann organizer. The dorsal blastopore "lip" of an early amphibian embryo can induce a second embryonic axis and embryo when transplanted to the ventral region of a recipient embryo. (b) In the developing chick vertebral limb bud, the zone of polarizing activity (ZPA) organizes pattern along the anteroposterior axis. Transplantation of the ZPA from a posterior to anterior position induces extra digits with reverse polarity.
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