Given their respective roles, why might activation of formin and myosin II be beneficial as cells assemble a functional contractile ring structure?
Oogenesis
The formation of the ovum (mature female gamete) from undifferentiated germ cells is called oogenesis. This process takes place in the ovaries (female gonads). Oogenesis consists of three stages known as the multiplication phase, growth phase, and maturation phase.
Cell Division
Cell division involves the formation of new daughter cells from the parent cells. It is a part of the cell cycle that takes place in both prokaryotic and eukaryotic organisms. Cell division is required for three main reasons:
In normally dividing cells, once chromosomes have been properly segregated via the steps of mitosis, the two resulting “daughter cells” separate. In animal cells (and other cell types without a cell wall) the contractile ring plays a crucial role in the process of cytokinesis. Exactly how the contractile ring is accurately positioned, so as to be located midway between the two poles (ends) of the dividing cell, is still not fully understood, although factors released from the mitotic spindle are thought to play a role.Regardless of the precise positioning mechanism, one key player in the assembly of the contractile ring is the GTP/GDP binding protein Rho. In its active form, Rho can stimulate the activity of the actin-binding protein formin and (via effects on the myosin regulatory light chain) that of myosin II. Given their respective roles, why might activation of formin and myosin II be beneficial as cells assemble a functional contractile ring structure?
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