ONA strands separate for replication. 2 Thymine on the original template strand base pairs with guanine through wabble, leading to an incorporated error. TTCG Wild type TTCG AAGC TTCG Mutant TTC AAGC Wild type TCCG AGGC DNA AGGC Wild type TTCG AAGC |At the next round of replication, the guanine nucleotide pairs with cytosine, leading to a transition mutation. AAGC 18.11 Wobble base pairing may lead to a replicated error.

Q: A monohybrid cross is a mating where alleles of just one gene are tracked in the offspring.  A test…

A: A test cross helps to determine or check the zygosity of a particular individual. In this type of…

Q: Given the following Wild Type and Mutated DNA sequences: 1.) Identify where the base pair change…

A: Mutations are the abrupt changes in the DNA sequences due to wrong reading of the DNA polymerase…

Q: Why do adult human cells (other than germ cells and stem cells) NOT express the enzyme telomerase?…

A: Telomerase expression is required for cell immortalization ( in cancer cells) and long term tumour…

Q: Why might some cells in the body, such as those in bonemarrow, be more susceptible to ribosomal…

A: Mutation It is the sudden heritable changes happening in the genotype of the organism which is…

Q: Eukaryotes have repair systems that prevent mutations due to copying errors and exposure to…

A: Eukaryotic cells are complex and multicellular in nature. It consists of a true nucleus, that is the…

Q: People with a commonly occurring, wild type allele of PTC with two adjacent thymines at a particular…

A: Part a.) :-ans.The presence of two adjacent thymines at a specific site in the PTC coding sequence…

Q: Based on the sequence data in the figure above, would you consider the patient to be not affected,…

A: Based on the information provided in the figure above, it can be concluded that the patient is…

Q: 1. Epigenetic marks refer to modifications to DNA and proteins that in tum regulate gene expression.…

A: Different macromolecules are present in humans. They include carbohydrates, lipids, proteins, and…

Q: Two possible point mutations are the substitution of lysine for leucine or the substitution of…

A: Amino acid mutations refer to changes in the DNA sequence that result in alterations to the sequence…

Q: Many of the gene products involved in DNA synthesis were initially defined by studying mutant E.…

A: During DNA replication another copy of DNA is synthesized on DNA template strand using Polymerase…

Q: Recent data indicate, as mentioned in the text, that the signal for eukaryotic mismatch repair, for…

A: The process of DNA synthesis is also known as DNA replication wherein a new daughter DNA molecule is…

Q: When the mismatch repair system detects a distortion in the DNA double helix due to a mismatch, what…

A: In the process of DNA (deoxyribonucleic acid) replication, DNA of the cell replicates itself while…

Q: What would happen to DNA repair in bacteria if MutH is mutated such that is cannot recognize the…

A: In prokaryotes , Mut H involved in mismatch repair syatem.  Mut S can recognise mismatched…

Q: DNA repair processes use the old DNA strand as the template to repair mismatched bases on the newly…

A: The basis of evolution is mutation. Mutation is also the basis of natural selection. Considerable…

Q: Given the Following DNA template, TAC   CGC   TCC   GCC  GTC   GAC   AAT   ACC   ACT, write out the…

A: The DNA template is used for the synthesis of mRNA molecules. mRNA molecule is used by the…

Q: What does it mean to say that extensions by DNA polymerase III proceeds 5' to 3'?

A: DNA replication is a process through which a new copy of DNA is synthesized. DNA polymerase III is…

Q: (a) How does the duplication of individual genes occur? (b) individual that inherit a genetic…

A: Mutation in the DNA can change our genetic material that can causes changes in our phenotype as…

Q: The enzyme telomerase is part protein and part RNA. What would be the most likely effect of a large…

A: Introduction  Ageing of cells can be attributed to several factors such as degradation of cellular…

Q: Some viruses, such as SV40, contain closed circular DNAs carrying nucleosomes. If the SV40 viral…

A: As we know that viral chromosome is circular in a structure having supercoiled DNA. This…

Tissue regeneration & repair

Tissue regeneration involves the restoration of tissue components by regrowth of damaged tissues. In contrast, tissue repair involves patching of injured tissue rather than restoring it. It is the proliferative capacity of the cells that decides the amount of regeneration against the repair that would occur in the tissue. Both regeneration and repair depending on the duration of the injury and response to the inflammation.