8. In patients with Albright-Butler syndrome (kidney acıdosis) seeretion of H into distal tubule lumen is damaged. It is noted polyuria, increased excretion of sodium and potassium (that leads to hyponatremia and hypokalemia), hypocalcemia and ostcoporosis, and decreased ammonia salt excretion, as well. What are the biochemical mechanisms of present symptoms development? For the answer: a) specify the enzyme the amount and activity of which is increased in kidney in acidosis under physiological norm;
8. In patients with Albright-Butler syndrome (kidney acıdosis) seeretion of H into distal tubule lumen is damaged. It is noted polyuria, increased excretion of sodium and potassium (that leads to hyponatremia and hypokalemia), hypocalcemia and ostcoporosis, and decreased ammonia salt excretion, as well. What are the biochemical mechanisms of present symptoms development? For the answer: a) specify the enzyme the amount and activity of which is increased in kidney in acidosis under physiological norm;
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Transcribed Image Text:8. In patients with Albright-Butler syndrome (kidney acidosis) secretion of H*
into distal tubule lumen is damaged. It is noted polyuria, increased excretion
of sodium and potassium (that leads to hyponatremia and hypokalemia),
hypocalcemia and ostcoporosis, and decreased ammonia salt excretion, as well.
What are the biochemical mechanisms of present symptoms development? For
the answer:
a) specify the enzyme the amount and activity of which is increased in kidney in
acidosis under physiological norm;
8.4. Synthesis of Nonessential Amino Acids
431
b) write down the reaction catalyzed by this enzyme and explain its physiological
significance;
c) point out the reasons for acidosis development and increased loss of sodium
and potassium in given disorder;
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