2. In a study, cats were fasted overnight then given a single meal complete in all amino acids except arginine. Within 2 hours, blood ammonia levels increased from a normal level of 94 umol/L to 470 umol/L, and the cats showed the clinical symptoms of ammonia toxicity. A control group fed a complete amino acid diet, or an amino acid diet, in which arginine was replaced by ornithine showed no unusual clinical symptoms. What causcd the ammonia levels to rise in the experimental group? Is arginine an essential amino acid in cats? Why or why not? For the answer: a) point out the role of fasting in the experiment; b) explain, why the absence of arginine can lead to ammonia toxicity; c) explain, the possibility of arginine substitution by ornithine; d) present the particular schemes to confirm your answer. ep

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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2. In a study, cats were fasted overnight then given a single meal complete in all
amino acids except arginine. Within 2 hours, blood ammonia levels inereased
from a normal level of 94 umol/L to 470 umol/L, and the cats showed
the clinical symptoms of ammonia toxicity. A control group fed a complete amino
acid diet, or an amino acid diet, in which arginine was replaced by ornithine
showed no unusual clinical symptoms. What caused the ammonia levels to rise
in the experimental group? Is arginine an essential amino acid in cats? WI
why not? For the answer:
a) point out the role of fasting in the experiment;
b) explain, why the absence of arginine can lead to ammonia toxicity;
c) explain, the possibility of arginine substitution by ornithine;
d) present the particular schemes to confirm your answer.
or
ep
Transcribed Image Text:2. In a study, cats were fasted overnight then given a single meal complete in all amino acids except arginine. Within 2 hours, blood ammonia levels inereased from a normal level of 94 umol/L to 470 umol/L, and the cats showed the clinical symptoms of ammonia toxicity. A control group fed a complete amino acid diet, or an amino acid diet, in which arginine was replaced by ornithine showed no unusual clinical symptoms. What caused the ammonia levels to rise in the experimental group? Is arginine an essential amino acid in cats? WI why not? For the answer: a) point out the role of fasting in the experiment; b) explain, why the absence of arginine can lead to ammonia toxicity; c) explain, the possibility of arginine substitution by ornithine; d) present the particular schemes to confirm your answer. or ep
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