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- 1. Differentiate the acute leukemias from the chronic leukemias as to: a. maturational stage of cells that predominate in blood / bone marrow. b. chronologic type( life expectancy after diagnosis) 2. Contrast the bases of FAB classification of leukemias from the bases of WHO classification. 3. The stain for esterases are useful in differentiating 2 types of AML. Why do you think this is more valuable in differentiating myelogenous/granulocytic from monocytic cells.What recent advancements in hematology research have shed light on the role of non-coding RNA molecules in regulating hematopoiesis and hematological disorders?A three-agent dosage regimen, termed VAD, for the treatment of multiple myeloma includes the following drugs taken over a 28-day cycle: Vincristine 0.4 mg/day, by IV infusion, D1-4 Doxorubicin 9 mg/m2/day, by IV infusion, D1-4 Dexamethasone 40 mg/day, PO, D1-4, 9-12, 17-20 Calculate the total quantity of doxorubicin administered over the course of the treatment cycle for a patient weighing 232 lbs and measuring 5' 7" in height. Round your answer to the nearest tenth. Express your answer as numbers only, no units.
- Explain two reasons for carrying out myeloablative therapy in hematopoietic stem cell recipients.1.2 Mr Juju verbalises that he was vaccinated for corona viruses two weeks ago 1.2.1. Explain the role of antibodies following vaccination 1.3 A week later: Mr Juju presents with Blood Glucose of 17.8mm/dl and blood pressure of 90/50mmHg 1.3.1. Describe the action insulin in response to elevated blood glucose to maintain blood glucose to normal ranges 1.3.2. Explain the influence of hormonal regulation to maintain normal blood pressure under the following: 1.3.2.1. Renin-angiotensin-aldosterone system (RAAS) 1.3.2.2. Atrial natriuretic peptide (ANP)What are the causes of thrombophilia? Describe the laboratory tests that are used to confirm the molecular cause of the condition in a patient.
- 1:e 66 of 145 88. A 57-year-old woman with a long history of chronic hepatitis B infection has the recent development of an avascular hepatocellular carcinoma. A CT scan is shown in which the tumor indicated by the arrows does not contain any contrast medium whereas the remainder of the liver does. Into which of the following arteries was the contrast medium most likely injected? OA) Femoral B) Gastroduodenal OC) Left hepatic Gross Anatomy D) Proper hepatic OE) Superior mesentericCan PCOS go away without treatment? If not, what happens if PCOS is left untreated? Note: Make the explanation simple and direct to the point.1. Differentiate leukemia from lymphoma and myeloma as to: a. hallmark cells / blood features b. organ in the body affected 2. In the 6 factors related to the occurrence of leukemia, rank them in order in which you think is the most related (1 for most related, 6 for least related). Give the reason for your ranking. 3. Rationalize why most leukemic patient die of infection. 4. In patients with leukemia, there is fatigue, weight loss, easy bruisability. Why do you think this is so?
- Explain the following statements in 4-6 lines each: Premalignant (hyperplastic or dysplastic) cells are probably present in the organs of the body of a normal (not suffering from cancer) person.A70-year-old woman with a long history of systemic lupus erythematosus has been receiving prednisone for the past 3 months. She also has been receiving captopril to treat her hypertension. Which of the following laboratory results would be evident in this patient? ???? ?????? ?? ????? ?? ???? ???????? a. Hyperglycemia b. Hyponatremia c. Hypercalcemia d. Hypocholesterolemia e. HypokalemiaThe following complete blood count (CBC) is completed for a client with chemotherapy-induced bone marrow suppression include: hemogiobin of 8.2 g/dL, hematocrit of 29%, platelet count of 160,000/ul, and white blood cell count of 2500/µL. The client was placed on filgrastim (Neupogen) 480 mcg SQ for 2 weeks. Which laboratory finding indicates that this therapy is effective? O The client's hemoglobin is 8.6 g/dL The client's hematocrit is > than 30% O The client's white blood cell is 3500/µl The client's platelet count is 165,000/µL
