A liquid/liquid extraction is performedto separate the following drug from aurine sample: Ibuprofen.The drug has a pka of 4.43+0.03 andan n-octanol/water partition coefficientof 11.7 at pH 7.4.1. Assume you have a 20nMconcentration of the drug in urine. Youperform a liquid/liquid extraction of20mL of urine with 10 mL of octanol atpH 7.4. What is your percent recovery?2. Would your recovery be higher orlower at pH 2.0?3. Explain what steps you would useto extract the drug by solid phaseextraction.7:55 PM V

The urine formation as, glomerular filtration, tubular reabsorption tubular secretion

Answered: of 4.43±0. partition c

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Chemistry

of 4.43±0. partition c

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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