но HO OH benzyl salicylate PolyAspirin но° он .CI salicylic acid sebacic acid sebacoyl chloride

Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter18: Carboxylic Acids
Section: Chapter Questions
Problem 18.21P
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Researchers at Rutgers University have developed biocompatible polymers that degrade into nonsteroidal antiinammatory drugs. For example, the reaction of two equivalents of benzyl salicylate and one equivalent of sebacoyl chloride forms a poly(anhydride ester) called PolyAspirin, which hydrolyzes to salicylic acid (an anti-inammatory agent) and sebacic acid, which is excreted. This technology can perhaps be used for localized drug delivery at specic sites of injury. What is the structure of PolyAspirin?

но
HO
OH
benzyl salicylate
PolyAspirin
но°
он
.CI
salicylic acid
sebacic acid
sebacoyl chloride
Transcribed Image Text:но HO OH benzyl salicylate PolyAspirin но° он .CI salicylic acid sebacic acid sebacoyl chloride
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