Nicotine patches are often used to help smokers quit. Does giving medicine to fight depression also help? A randomized double-blind experiment assigned 244 smokers to receive nicotine patches and another 245 to receive both a patch and the antidepressant drug bupropion. After a year, 40 subjects in the nicotine patch group had abstained from smoking, as had 87 in the patch-plus-drug group. (a) Construct and interpret a 99% confidence interval for the difference in the proportion of smokers who abstain when using buproprion and a nicotine patch and the proportion who abstain when using only a patch. (b) Based only on this interval, do you think that the difference in proportion of abstaining smokers is significant? Justify your answer.
Nicotine patches are often used to help smokers quit. Does giving medicine to fight depression
also help? A randomized double-blind experiment assigned 244 smokers to receive nicotine
patches and another 245 to receive both a patch and the antidepressant drug bupropion. After a
year, 40 subjects in the nicotine patch group had abstained from smoking, as had 87 in the
patch-plus-drug group.
(a) Construct and interpret a 99% confidence interval for the difference in the proportion of
smokers who abstain when using buproprion and a nicotine patch and the proportion who
abstain when using only a patch.
(b) Based only on this interval, do you think that the difference in proportion of abstaining
smokers is significant? Justify your answer.
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