NADH + H* NAD+ но н HC-C-C-C00 HC-C-C-C00 a-Amino-B-ketobutyrate Threonine H3C-CH Acetaldehyde CoA- COA7 HC-C-SCOA Acetyl-CoA H-C-C00 NH Glycine NADH + NH + CO, NN0.Methylene-THF NAD* + NH- CH,-C00 Glyeine THF HS H H но н H2C-C-CoO NH H3C-C-Co0 NH HC-C-co NH Cysteine Alanine Serine a-Ketoglutarate e, several paths Glutamate (H,S, so, or SCN NH3 ine H3C-C-CO0 NH3 Руruvate

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Mouse embryonic stem cells divide extremely rapidly, about once every 5 hours. These cells require large amounts of threonine in their medium. Explain how threonine catabolism (Fig.) helps meet the cells’ energy needs and their high rate of DNA synthesis.

NADH + H*
NAD+
но н
HC-C-C-C00
HC-C-C-C00
a-Amino-B-ketobutyrate
Threonine
H3C-CH
Acetaldehyde
CoA-
COA7
HC-C-SCOA
Acetyl-CoA
H-C-C00
NH
Glycine
NADH + NH + CO,
NN0.Methylene-THF
NAD* + NH- CH,-C00
Glyeine
THF
HS H
H
но н
H2C-C-CoO
NH
H3C-C-Co0
NH
HC-C-co
NH
Cysteine
Alanine
Serine
a-Ketoglutarate
e,
several
paths
Glutamate
(H,S, so, or SCN
NH3
ine
H3C-C-CO0
NH3
Руruvate
Transcribed Image Text:NADH + H* NAD+ но н HC-C-C-C00 HC-C-C-C00 a-Amino-B-ketobutyrate Threonine H3C-CH Acetaldehyde CoA- COA7 HC-C-SCOA Acetyl-CoA H-C-C00 NH Glycine NADH + NH + CO, NN0.Methylene-THF NAD* + NH- CH,-C00 Glyeine THF HS H H но н H2C-C-CoO NH H3C-C-Co0 NH HC-C-co NH Cysteine Alanine Serine a-Ketoglutarate e, several paths Glutamate (H,S, so, or SCN NH3 ine H3C-C-CO0 NH3 Руruvate
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