Methanol and ethanol bind to the same active site on the enzyme alcohol dehydrogenase (ADH) to undergo oxidation, as shown in the equations below. In methanol poisoning, ethanol is given intravenously to prevent the formation of formaldehyde that has toxic effects. In this scenario, what type of inhibitor is ethanol with regard to alcohol dehydrogenase catalyzing the oxidation of methanol? CH3-OH + NAD CH3-CH2-OH + NAD+ H* ADH O a competitive inhibitor HCHO+NADH + H+ ADH CH3-CHO+NADH + O a noncompetitive inhibitor O both a noncompetitive and an irreversible inhibitor O an irreversible inhibitor

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GR
Methanol and ethanol bind to the same active site on the enzyme
alcohol dehydrogenase (ADH) to undergo oxidation, as shown in
the equations below. In methanol poisoning, ethanol is given
intravenously to prevent the formation of formaldehyde that has
toxic effects. In this scenario, what type of inhibitor is ethanol with
regard to alcohol dehydrogenase catalyzing the oxidation of
methanol?
budy
CH3-OH + NAD+
HCHO+NADH + H+
CH3-CH2-OH + NAD+ CH3-CHO + NADH +
H*
O a competitive inhibitor
ADH
O an irreversible inhibitor
ADH
O a noncompetitive inhibitor
O both a noncompetitive and an irreversible inhibitor
O Sea
hp
Transcribed Image Text:GR Methanol and ethanol bind to the same active site on the enzyme alcohol dehydrogenase (ADH) to undergo oxidation, as shown in the equations below. In methanol poisoning, ethanol is given intravenously to prevent the formation of formaldehyde that has toxic effects. In this scenario, what type of inhibitor is ethanol with regard to alcohol dehydrogenase catalyzing the oxidation of methanol? budy CH3-OH + NAD+ HCHO+NADH + H+ CH3-CH2-OH + NAD+ CH3-CHO + NADH + H* O a competitive inhibitor ADH O an irreversible inhibitor ADH O a noncompetitive inhibitor O both a noncompetitive and an irreversible inhibitor O Sea hp
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