Membrane Na Inside Coulomb force Diffusion Outside Coulomb force Diffusion Coulomb force Diffusion Figure 20.28 The semipemeable membrane of a cell has different concentrations of ions inside and out. Diffusion moves the K* and Cl' ions in the direction shown, until the Coulomb force halts further transfer. This results in a layer of positive charge on the outside, a layer of negative charge on the inside, and thus a voltage across the cell membrane. The membrane is normally impermeable to Na*.

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