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Match to the correct term by dragging-and-dropping the words below: Glucuronidation Hydroxylation Liver/gut mucosa Process of adding hydrophilic group(s) to drug/metabolite molecule, to allow drug/metabolite excretion in the urine Prodrug P glycoprotein Enterohepatic cycling Process converting lipophilic drug to more polar molecule by unmasking or adding a polar functional grou Process of forming multiple bonds between molecules and a transition metal ion, leading to sequestration the metal Drug-nutrient interaction

Match to the correct term by dragging-and-dropping the words below: Glucuronidation Hydroxylation Liver/gut mucosa Process of adding hydrophilic group(s) to drug/metabolite molecule, to allow drug/metabolite excretion in the urine Prodrug P glycoprotein Enterohepatic cycling Process converting lipophilic drug to more polar molecule by unmasking or adding a polar functional grou Process of forming multiple bonds between molecules and a transition metal ion, leading to sequestration the metal Drug-nutrient interaction

Phlebotomy Essentials
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
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Phase II metabolism Transport intracellular drugs across the cell membrane to outside the cell Major process catalyzed by P450 enzymes Phase I metabolism Chelation Drug/metabolite excreted into bile, released into gut, then reabsorbed into blood Conjugation reaction to allow for drug/metabolite excretion in bile or urine Chemical that requires conversion to an active drug Major biotransformation & conjugation site Alteration of drug pharmacokinetics or pharmacodynamics caused by presence of food
Transcribed Image Text:Phase II metabolism Transport intracellular drugs across the cell membrane to outside the cell Major process catalyzed by P450 enzymes Phase I metabolism Chelation Drug/metabolite excreted into bile, released into gut, then reabsorbed into blood Conjugation reaction to allow for drug/metabolite excretion in bile or urine Chemical that requires conversion to an active drug Major biotransformation & conjugation site Alteration of drug pharmacokinetics or pharmacodynamics caused by presence of food
Match to the correct term by dragging-and-dropping the words below: Glucuronidation Hydroxylation Liver/gut mucosa Process of adding hydrophilic group(s) to drug/metabolite molecule, to allow drug/metabolite excretion in the urine Prodrug P glycoprotein Enterohepatic cycling Process converting lipophilic drug to more polar molecule by unmasking or adding a polar functional group Process of forming multiple bonds between molecules and a transition metal ion, leading to sequestration of the metal Drug-nutrient interaction
Transcribed Image Text:Match to the correct term by dragging-and-dropping the words below: Glucuronidation Hydroxylation Liver/gut mucosa Process of adding hydrophilic group(s) to drug/metabolite molecule, to allow drug/metabolite excretion in the urine Prodrug P glycoprotein Enterohepatic cycling Process converting lipophilic drug to more polar molecule by unmasking or adding a polar functional group Process of forming multiple bonds between molecules and a transition metal ion, leading to sequestration of the metal Drug-nutrient interaction
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