Mary Alexander studied the effects of radiation on mutation rates in he sperm of Drosophila melanogaster. She exposed Drosophila larvae to either 3000 roentgens (r) or 3975 r of radiation, collected the adult males that developed from irradiated larvae, and mated them with nonirradiated females that were homozygous for recessive alleles at eight loci. She then counted the number of F, flies that carried a new mutation at each locus. All mutant flies that appeared were used in subsequent crosses to determine if their mutant phenotypes were heritable. For the roughoid locus, she obtained the following results (M. L. Alexander. 1954. Genetics 39:409-428): Number of Offspring with a mutation at offspring Group the roughoid locus Control (0 r) Irradiated 45,504 49,512 (3000 r) Irradiated 50,159 16 (3975 r)

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Calculate the mutation rates at the roughoid locus for the control group and the two groups of irradiated flies.

Mary Alexander studied the effects of radiation on mutation rates in
he sperm of Drosophila melanogaster. She exposed Drosophila larvae
to either 3000 roentgens (r) or 3975 r of radiation, collected the adult
males that developed from irradiated larvae, and mated them with
nonirradiated females that were homozygous for recessive alleles at
eight loci. She then counted the number of F, flies that carried a new
mutation at each locus. All mutant flies that appeared were used in
subsequent crosses to determine if their mutant phenotypes were
heritable. For the roughoid locus, she obtained the following results (M.
L. Alexander. 1954. Genetics 39:409-428):
Number of Offspring with a mutation at
offspring
Group
the roughoid locus
Control (0
r)
Irradiated
45,504
49,512
(3000 r)
Irradiated
50,159
16
(3975 r)
Transcribed Image Text:Mary Alexander studied the effects of radiation on mutation rates in he sperm of Drosophila melanogaster. She exposed Drosophila larvae to either 3000 roentgens (r) or 3975 r of radiation, collected the adult males that developed from irradiated larvae, and mated them with nonirradiated females that were homozygous for recessive alleles at eight loci. She then counted the number of F, flies that carried a new mutation at each locus. All mutant flies that appeared were used in subsequent crosses to determine if their mutant phenotypes were heritable. For the roughoid locus, she obtained the following results (M. L. Alexander. 1954. Genetics 39:409-428): Number of Offspring with a mutation at offspring Group the roughoid locus Control (0 r) Irradiated 45,504 49,512 (3000 r) Irradiated 50,159 16 (3975 r)
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