Malate dehydrogenase catalyzes the oxidation of malate to oxaloacetate with a standard Gibbs free energy of AG° +29.7 What is the equilibrium constant (Keq) for this = mol reaction at 298 K and pH 7? Under physiological conditions at 310 K and pH 7, this reaction is at equilibrium. In the mitochondrial matrix, the ratio NAD+/NADH is 8 and the concentration of malate is 1.0 mM. What is the concentration of oxaloacetate? Malate dehydrogenase is also present in the cytoplasm where the ratio NAD+/NADH is 700 and malate concentration is 1.0 mM. If this reaction is at equilibrium at 310 K and pH 7, what is the cytosolic concentration of oxaloacetate? malate + NAD+ oxaloacetate + NADH + H+
Malate dehydrogenase catalyzes the oxidation of malate to oxaloacetate with a standard Gibbs free energy of AG° +29.7 What is the equilibrium constant (Keq) for this = mol reaction at 298 K and pH 7? Under physiological conditions at 310 K and pH 7, this reaction is at equilibrium. In the mitochondrial matrix, the ratio NAD+/NADH is 8 and the concentration of malate is 1.0 mM. What is the concentration of oxaloacetate? Malate dehydrogenase is also present in the cytoplasm where the ratio NAD+/NADH is 700 and malate concentration is 1.0 mM. If this reaction is at equilibrium at 310 K and pH 7, what is the cytosolic concentration of oxaloacetate? malate + NAD+ oxaloacetate + NADH + H+
Chemistry: Principles and Reactions
8th Edition
ISBN:9781305079373
Author:William L. Masterton, Cecile N. Hurley
Publisher:William L. Masterton, Cecile N. Hurley
Chapter23: Organic Polymers, Natural And Synthetic
Section: Chapter Questions
Problem 46QAP: Glycolysis is the process by which glucose is metabolized to lactic acid according to the equation...
Related questions
Question
None

Transcribed Image Text:Malate dehydrogenase catalyzes the oxidation of malate to oxaloacetate with a standard
Gibbs free energy of AG° +29.7 What is the equilibrium constant (Keq) for this
=
mol
reaction at 298 K and pH 7? Under physiological conditions at 310 K and pH 7, this
reaction is at equilibrium. In the mitochondrial matrix, the ratio NAD+/NADH is 8 and
the concentration of malate is 1.0 mM. What is the concentration of oxaloacetate? Malate
dehydrogenase is also present in the cytoplasm where the ratio NAD+/NADH is 700 and
malate concentration is 1.0 mM. If this reaction is at equilibrium at 310 K and pH 7, what
is the cytosolic concentration of oxaloacetate?
malate + NAD+ oxaloacetate + NADH + H+
Expert Solution

This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
Step by step
Solved in 2 steps

Recommended textbooks for you

Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning

Introduction to General, Organic and Biochemistry
Chemistry
ISBN:
9781285869759
Author:
Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:
Cengage Learning

Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning

Introduction to General, Organic and Biochemistry
Chemistry
ISBN:
9781285869759
Author:
Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:
Cengage Learning