Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shows. (BENZENE -> 2-ACETOXYBENZOIC ACID or ASPIRIN)

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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shows. (BENZENE -> 2-ACETOXYBENZOIC ACID or ASPIRIN)

Kolbe-Schmidt
SO3H
ONa
reaction
ОН О
H2SO4
NaOH
CO2, H20
OH Acetic anhydride
HO,
Benzene
Sodium
Salicylic acid
Aspirin
phenolate
Transcribed Image Text:Kolbe-Schmidt SO3H ONa reaction ОН О H2SO4 NaOH CO2, H20 OH Acetic anhydride HO, Benzene Sodium Salicylic acid Aspirin phenolate
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