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![Apply multistep retrosynthetic analysis to the target molecule shown in
Figure 5 and explain your answer.
H₂N-](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fcd105e17-9294-4ff4-a61d-a23695d380c9%2Ff0e31efe-ce9f-4f22-9924-ad8667b3db68%2Fxp6onhp_processed.jpeg&w=3840&q=75)
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- identify which structural effect predominantly accounts for each given observation or phenomenon. Choose your answers from the following: A = Resonance B = C-H hyperconjugation C = Inductive Effect D = Steric Effect All ortho-substituted benzoic acid compounds have lower pka values than benzoic acid itself.S=C=N Ph P(OPh)2 Please provide a retrosynthetic analysis for this molecule3 The 1H- and 13C-NMR data of an ester of molecular formula C6H10O2 are given below. Also shown are the COSY and HETCOR NMR spectra of the ester. Identify the ester, explaining how you reach your conclusion. 1H-NMR: 7.20-6.90 (1H), 5.85 (1H), 4.16 (2H), 1.88 (3H), 1.31 (3H) ppm 13C-NMR: 166.7, 144.5, 123.0 , 60.2, 18.0, 14.3 ppm
- Which of these compounds would not show up on a TLC plate under a UV lamp? ○ All of these compounds will show up under UV. ○ 2-bromoacetanilide Phenylacetic acid O 2-Chlorobenzoic acid ○ Propyl 4-hydroxybenzoateSuggest a forward synthesis for the following retrosynthetic analysis of the target molecule. Begin with the labeled starting material and be sure to include the synthetic equivalent (SE-1) in your synthesis. Target Molecule EtO₂C SE-1 CO₂Et EtO₂C CO₂Et Starting MaterialDCC H3C ངོན་དྲིས" ",, CH3 CH3 Treatment of an α-amino acid such as alanine with DCC yields a 2,5-diketopiperazine. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions HN CH3 :0: CH3 NH HN :O: H3C N H-A NH HN CH3
- what is the structure of o-methylphenoxide anion and what is its pKa?Explain why a proton can be removed from the 'alpha-carbon of N,N-dimethylethanamide but not from the alpha-carbon of either N-methylethanamide or ethanamide.Draw the structure of the compound whose data is shown below. Upload your answer to receive full credit. C9H,NO3 There are 7 C-NMR signals. The compound is significantly deactivated toward electrophilic aromatic substitution. H-NMR: 12.7 ppm, s, 1H 10.3 ppm, s 1H 7.91 ppm, d, 2H 7.72 ppm, d, 2H 2.10 ppm, s 3H
- In the acid-catalyzed dehydration of 2-methyl-1-propanol, what carbocation would be formed if a hydride shift accompanied cleavage of the carbon–oxygen bond in the alkyloxonium ion? What ion would be formed as a result of a methyl shift? Which pathway do you think will predominate, a hydride shift or a methyl shift?1 (a) Which of the following chemical tests can differentiate acetanilide from acetic anhydride? Nitration Lucas test Hydrolysis with litmus test Hinsberg test (b) Which of the following chemical tests can differentiate acetanilide from aniline? Hinsberg test Hydrolysis with litmus test Nitration Lucas testPilocarpine is a medication used in eye drop to manage angle closure glaucoma. It works by activating cholinergic receptors of the muscarinic type which cause the trabecular meshwork to open and the aqueous humor to drain from the eye. The diester compound in the left can serve as a prodrug for pilocarpine. Please provide a mechanism for this conversion using esterase. R2 pilocarpine Diester prodrug for pilocarpine
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