Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shown. (Synthesis of Caffeine from Uric Acid)

Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shown. (Synthesis of Caffeine from Uric Acid)

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

See similar textbooks

Related questions

Q: Which is the organic product for the following reaction? KMnO4 H₂O

A: The alkyl group attached to the benzene ring having at least one hydrogen atom at the key atom can…

Q: help please answer in text form with proper workings and explanation for each and every part and…

A: Here pyridine act as a base that abstracts the proton from the secondary amine to develop a negative…

Q: Give a clear handwritten answer with explanation...give the mechanism of all sub parts reactions…

A: 1) SN2 mechanism: Concerted mechanism with inversion of configuration 2) E2 mechanism: Concerted…

Q: Draw the structure of propyl (5E)-8-hydroxyoct-5-enoate.

A: Given,The name of the molecule is:propyl (5E)-8-hydroxyoct-5-enoate

Q: 20. What is the major product for the following reaction? EtONa, EtOH A) B) D) heat E) None of these…

A: -> EtONa is base which can abstract most acidic beta hydrogen to give alkene.-> EtONa is not a…

Q: Show the electron-flow mechanism of the chosen synthetic schemes. This involves predicting major and…

A: Benzene Sulfonic Acid to Phenol

Q: HNO3/H₂SO4 OH -NHCCH3 pla Cl₂/AICI 3 CH3CI/AICI 3

A: In polysubstituted functional groups electron releasing group controls the orientationCarbonyl…

Q: 3) Propose a synthesis for the below transformation using only structure A as a source of carbon…

A: To carry out the given synthesis, the below-given type of reactions are usedEpoxidation reaction of…

Q: Q1. What is the product of the reaction shown below? CH₂CH3 HNO3 H₂SO4

A: In an aromatic electrophilic substitution reaction, an electrophile attacks the benzene rings and…

Q: 2H.) Provide missing product(s) in the box 1.) HⓇ mild H₂N-CH3 2.) LiAlH4 + 3.) H30

Q: Draw the major product of this reaction. Ignore inorganic byproducts. Assume that the water side…

A: Carbonyl compounds are reactive due to the presence of O=C group. They prefer to undergo…

Q: 5. Rank the compounds below according to their reactivity toward electrophilic aromatic…

A: In electrophilic aromtic substituion an electrophile attacks the nucleophilic (electron rich…

Q: ive detailed Solution with explanation needed

A: Alkynes on hydration reaction gives an enol which on tautomerism to form the carbonyl compounds.

Q: Outline a synthesis for the following compound from the indicated starting material and any other…

A: In the given question we have to write the synthesis of the given molecule from the given starting…

Q: Draw the major organic product formed in the reaction. The starting material is a carbonyl bonded to…

A: We have to draw the major organic product of the below given reaction. Introduction: Bromination…

Q: erform the retrosynthesis (with its structures) and the synthetic route of the molecule below f

A: Given is organic compound. To find out starting compound let's perform retrosynthetic analysis of…

Q: Synthesize the following molecule below starting from formaldehyde and alcohols of 4 carbons or less…

A: The given molecule is synthesized from formaldehyde and 4 carbon alcohol. The first step is the…

Q: What is the major product from the reaction shown? OH (A) H₂O -CH₂CH3 H

A: Alkene gives hydration reactions in presence of an acid catalyst. The reaction follows an…

Q: 5. What is the expected product of this reaction? CH₂CH₂CH3 CH3 Br₂, hv ? CHBRCH₂CH3 CH₂CHBRCH3 (A)…

Q: Give detailed mechanism Solution with explanation needed..no need handwritten answer

A: The given reagent is sodium amide in liquid ammonia.It can act as a base or nucleophile.In this…

Q: H ? OH

A: Given is organic reaction.

Q: Draw the organic product of the following reaction. CH3 CH₂ CH₂l2, Zn/Cu

A: The given reaction is an example of Simmon-smith reaction.

Q: Provide a complete synthetic scheme for the following compound starting from either malonic or…

A: The question is based on the concept of organic synthesis. we need to synthesize the product using…

Q: explain steps on how to identify ester functional group using hydroiodic acid (zeisel's alkoxy…

Q: Provide a synthesis, showing all intermediates. Use materials with no more than 7C. in

Q: Alcohols and mechanism with HBr Part A Complete the chemical equation for the substitution reaction…

Q: Draw the major organic product formed when the compound shown below is heated with H₂SO4.…

Q: Draw the predominant product(s) of the following reactions including stereochemistry when it is…

A: When alkene or Alkyne reacts with hydrogen halide it follow morkovnikov rule and nucleophilic part…

Q: Give the major organic product of the following series of reactions. b) c) d) 1) NaNH, 2) CH₂CH₂Br…

A: The question is based on organic reactions.We need to identify the product and explain its…

Q: Draw the structure of the major product in the following reaction: cyclopentanone reacted with 1.)…

A: Amine reacts with carbonyl compounds by a nucleophilic addition reaction mechanism. The product…

Q: Draw the major product of this reaction. Ignore inorganic byproducts. + H NO₂ NaOCH₂CH3 CH3CH₂OH

Q: Please aid in drawing mechanisms for the reactions shown below.

Q: HO I-Z 0 CH₂

A: The above desired product is paracetamol, also known as acetaminophen in the United States and…

Q: 1,2-Trans-cyclohexanediol has been shown to be an efficient support for the asymmetric…

A: PhLi can act as a nucleophile. It can undergo halogen exchange reaction to generate anion.

Q: Prepare 2-methoxy-propanol from 1- bromo-propane. Show the steps and use any reagents you need.

A: The detailed explanation of this question is given below

Q: 1. Write a curved arrow mechanism for the reaction below: HBr 0-01 -C=CH Br C -CH3 Br

A: We have to draw the mechanism of the given reaction.Given:

Q: Provide a synthesis of the target structure on the right from the starting structure on the left,…

A: The given synthesis scheme is shown below.We have to carry out the above synthesis.

Q: Provide a plausible arrow pushing mechanism for the reaction below. 1.1 eq. tBuOK 2. acidic workup

Q: Which statements are true regarding the reaction of 1-chlorohexane with sodium ethoxide in ethanol?…

A: Here 1-chlorohexane reacts with sodium ethoxide in ethanol.

Q: Suggest a synthesis of the following from benzene. You may use any additional reagents as necessary.…

A: Given organic synthesis reaction.

Q: What is the expected product of the following bro- mination of benzeneselenol? Justify your answer…

Q: SUGGEST A REASONABLE synthetic strategy for synthesis of 4-methyl-1, 4-pentanediol from methyl-4-…

A: Esters reacts with Alkyl magnesium bromide (Grignard reagent) to give ketone. Ketone on further…

Q: 9. Synthesis Using the carbon-containing starting material(s), propose a synthesis for both of the…

A: To get the starting molecule we have to do the retrosynthetic analysis and by doing this we get…

Q: Be sure to answer all parts. Draw a stepwise mechanism for the following transformation: O H3O H₂O…

A: Organic transformation

Question

Make an electron-flow-mechanism for this synthetic scheme. This involves predicting major and by-products using electronic and structural effects. The arrow push mechanism must be shown. (Synthesis of Caffeine from Uric Acid)

CH3
CH3
CH3N
N.
CH&N
N,
2[H]
POCI3
-HCI
A
'N'
N'
'N'
N.
CH3
CH3
Chlorocaffeine
Caffeine

H
CH3
CH3
HN
CH3N
N.
CH:N
CH3I
-ОН
NaOH
N'
N'
N-
N'
N'
N'
H
H
CH3
H
CH3
Uric Acid
1,3,7-Trimethyluric Acid
Enolic

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

This is a popular solution!

SEE SOLUTION Check out a sample Q&A here

Step 1

VIEW

Step 2

VIEW

Trending now

This is a popular solution!

Step by step

Solved in 2 steps with 2 images

SEE SOLUTION Check out a sample Q&A here

Similar questions

( plz do all plz and will upvote with explanation and mechanism plz give mechanism
Please don't provide andwritten solution ...
Give detailed mechanism Solution with explanation needed of each steps..don't give Handwritten answer.. I want detailed Solution
Give a clear explanation handwritten answer....give the all missing reagent to Complete the reactions....
Give detailed mechanism Solution with explanation needed..don't give Handwritten answer..what enol intermediate is formed in this reaction
Give detailed Solution with explanation needed..don't give Handwritten answer
Give a clear handwritten answer with explanation...give the mechanism of given bleow reaction and choose correct option
Give detailed Solution with explanation needed
Give a clear handwritten answer with explanation..give answer all sub parts
Outline a synthesis of the following compound from two equivalents of 1-methylcyclopentene as the only source of carbon and any needed inorganic reagents. HC -CH3 3 -CH3 from two equivalents of HINT: You will need both a cyclic acetal and a TMS ether protecting group.
With diagrams and detailed explanations, comment on the electrophilic aromatic substitution reactivity of quinoline and isoquinoline
Give the stepwise arrow-pushing mechanism for the following reaction to produce the product with stereochemical outcome.