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ly the cell cycle of human hepatocytes (i.e. cells from the main tissue of the culture a single hepatocyte from a tissue sample you have received. You the on over time under the stimulation of a growth factor. After a few rounds of u notice that cells divide progressively faster, have a smaller volume and div bly even in the absence of any growth factor. e following is consistent with this observation? G₂ checkpoint is functional but the G₁ checkpoint is non-functional G₁ checkpoint is functional but the G₂ checkpoint is non-functional Ras gene is mutated s undergo apoptosis s have entered the Go phase

ly the cell cycle of human hepatocytes (i.e. cells from the main tissue of the culture a single hepatocyte from a tissue sample you have received. You the on over time under the stimulation of a growth factor. After a few rounds of u notice that cells divide progressively faster, have a smaller volume and div bly even in the absence of any growth factor. e following is consistent with this observation? G₂ checkpoint is functional but the G₁ checkpoint is non-functional G₁ checkpoint is functional but the G₂ checkpoint is non-functional Ras gene is mutated s undergo apoptosis s have entered the Go phase

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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11. You study the cell cycle of human hepatocytes (i.e. cells from the main tissue of the liver). You isolate and culture a single hepatocyte from a tissue sample you have received. You then track the rate of cell division over time under the stimulation of a growth factor. After a few rounds of steady cell divisions, you notice that cells divide progressively faster, have a smaller volume and divide uncontrollably even in the absence of any growth factor. Which of the following is consistent with this observation? A. The G₂ checkpoint is functional but the G₁ checkpoint is non-functional B. The G₁ checkpoint is functional but the G₂ checkpoint is non-functional C. The Ras gene is mutated D. Cells undergo apoptosis E. Cells have entered the Go phase
Transcribed Image Text:11. You study the cell cycle of human hepatocytes (i.e. cells from the main tissue of the liver). You isolate and culture a single hepatocyte from a tissue sample you have received. You then track the rate of cell division over time under the stimulation of a growth factor. After a few rounds of steady cell divisions, you notice that cells divide progressively faster, have a smaller volume and divide uncontrollably even in the absence of any growth factor. Which of the following is consistent with this observation? A. The G₂ checkpoint is functional but the G₁ checkpoint is non-functional B. The G₁ checkpoint is functional but the G₂ checkpoint is non-functional C. The Ras gene is mutated D. Cells undergo apoptosis E. Cells have entered the Go phase
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