Answered: Keratinocytes are the predominant cell…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

Keratinocytes are the predominant cell type found in the epidermal layer. Knowing that many
of these cells die each day while an equal number are produced, you are interested in
understanding where they come from and how the population is maintained.
a) You collect a sample of keratinocytes and allow them to grow in cell culture. Though
the cells are visibly indistinguishable from each other, you find that some fail to divide
while others have formed large colonies. What might be different about the two types
of cells?
b) You take all the cells from one of the large colonies and grow them on a fresh plate.
You see some of the cells again form large colonies, but most fail to divide. Explain
these results.

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