(iv) Provide a detailed mechanism for the Claisen condensation reaction between L and M, and give the structure of product N. In your answer, indicate which step is responsible for driving the reaction to completion. MeO + A MeO OMe M NaOH(aq) (1) NaOMe (v) Identify reactant O required to react with ketone A in order to form a,ß-unsaturated ketone P. Explain the type of reaction taking place and draw the intermediate that under the reaction conditions undergoes formation of P (mechanisms not required). reflux (2) acidic work-up MeO N P
(iv) Provide a detailed mechanism for the Claisen condensation reaction between L and M, and give the structure of product N. In your answer, indicate which step is responsible for driving the reaction to completion. MeO + A MeO OMe M NaOH(aq) (1) NaOMe (v) Identify reactant O required to react with ketone A in order to form a,ß-unsaturated ketone P. Explain the type of reaction taking place and draw the intermediate that under the reaction conditions undergoes formation of P (mechanisms not required). reflux (2) acidic work-up MeO N P
Chapter22: Carbonyl Alpha-substitution Reactions
Section22.SE: Something Extra
Problem 20MP
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