Intermediary metabolism includes all the reactions in an organism involved in generating and storing metabolic energy, and with using that energy in the synthesis of low-molecular weight compounds and energy-storing compounds. Which of the following processes is not considered to be intermediary metabolism? degradation of glucose to two molecules of pyruvate synthesis of a 16-carbon fatty acid from 8 acetyl-CoA molecules synthesis of deoxyribonucleotides from ribonucleotides synthesis of mRNA by RNA polymerase II
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- Fatty acid synthesis is largely the reverse of beta oxidation, yet there are some distinct differences. From the statements below, which of the following is inaccurateconcerning fatty acid metabolism? Both processes use mobile electron carriers Both beta oxidation and fatty acid synthase use a carrier group The first step in fatty acid degradation pathway and biosynthetic pathway are regulated C2 unit of acetyl moiety is used in both fatty acid degradation and fatty acid biosynthesis Both processes occur in a unique, specific location (Compartmentalization)Which of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductaseWhich of the following statements is TRUE about fatty acid biosynthesis? Group of answer choices: NADH is used as the reducing equivalent in the process. Malonyl ACP is the donor of the acetyl group. The product detaches from the fatty acid synthase complex when the chain length is usually 18 carbons. Oxaloacetate carries acetyl CoA to the cytosol.
- During fatty acid synthesis, which of the below is the product of β-enoyl-ACP reductase:Which of the following statements is TRUE about fatty acid biosynthesis? Citrate carries malonyl CoA to the cytosol. O Acetyl ACP is the donor of the acetyl group. O NADPH is used as the reducing equivalent in the process. O The product detaches from the fatty acid synthase complex when the chain length is usually 18 carbons.Decide whether each of the following statements is true about leucine transaminase. It's an enzyme, and leucine is its substrate. It speeds up the rate at which leucine is converted to other substances. It's a small molecule, with a molecular weight around 50 mol If you were to write a chemical equation for certain biochemical reactions of leucine, leucine transaminase would appear on both sides. Otrue Ofalse Otrue Ofalse Otrue Ofalse Otrue Ofalse X
- Years ago there was interest in using uncouplers such as dinitrophenol as weight control agents. Presumably, fat could be oxidized without concomi- tant ATP synthesis for re-formation of fat or carbohydrate. Why was this a bad (i.e., fatal) idea?Identify different types of organic reaction mechanism (SN1, SN2, etc) and reaction types (addition, elimination, etc) in the following metabolic pathways. Catabolism of triacylglycerols- beta-oxidation pathway Biosynthesis of fatty acids from Acetyl CoA Glycolysis (from glucose to two molecules of pyruvate) Conversion of Pyruvate to Acetyl CoA Citric acid cycle Gluconeogenesis pathway (pyruvate to glucose)All of the following are accurate contrasts for beta oxidation vs fatty acid synthesis except which of the following statements? Group of answer choices The hydroxylacyl group differs in stereochemistry between beta oxidation and biosynthesis CoA is the acyl carrier group in beta oxidation, acyl carrier protein is the carrier in biosynthesis The carbon unit resulting from beta oxidation is acetyl-CoA, the carbon unit for biosynthesis is malonyl-CoA FAD is an electron acceptor in beta oxidation, NADP+ is the electron acceptor in biosynthesis
- In which of the following metabolic conversions is ATP “generated” during glycolysis? Glucose —> Glucose-6-phosphate 1,3-Bisphosphoglycerate —> 3-Phosphoglycerate Fructose-1,6-bisphosphate —> Dihydroxyacetone phosphate + Glyceraldehyde-3-phosphate Glucose-6-phosphate —> Fructose-6-phosphate 2-Phosphoglycerate —> 3-PhosphoglycerateStarting with a 4-carbon growing fatty acid attached to the ketoacyl synthase (KSase) site, and a malonate attached to the malonyl transferase (MTase) site in an animal fatty acid synthase (FAS) enzyme complex, draw the next reactions/events that result in the extension and processing of the fatty acid by two more carbons to make the saturated 6-carbon fatty acid.Part A Identify each of the following metabolic pathways. Drag the appropriate labels to their respective targets. Reset Help the conversion of fatty acids to 2-carbon units of acetyl CoA ketogenesis the conversion of an amino acid to an a-keto transamination acid the combination of 2-carbon units of acetyl COA to form fatty acids oxidative deamination the removal of an amino group as NH4+ from B oxidation glutamate to yield a-ketoglutarate lipogenesis the production of ketone bodies