In the situations described below, what is the free energy change if 1 mole of Na* is transported across a membrane from a region where the concentration is 1 µM to a region where it is 100 mM? (Assume T = 37 °C) (a) In the absence of a membrane potential. (b) When the transport is opposed by a membrane potential of 70 mV. (c) In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplamic concentrations: ATP = 4.60 mM, P; = 5.10 mM, ADP = 310 µM?

Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
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In the situations described below, what is the free energy change if
1 mole of Na* is transported across a membrane from a region
where the concentration is 1 µM to a region where it is 100 mM?
(Assume T = 37 °C)
(a) In the absence of a membrane potential.
(b) When the transport is opposed by a membrane potential of 70 mV.
(c) In each case, will hydrolysis of 1 mole of ATP suffice to drive
the transport of 1 mole of ion, assuming pH 7.4 and the following
cytoplamic concentrations: ATP = 4.60 mM, P; = 5.10 mM, ADP
= 310 µM?
Transcribed Image Text:In the situations described below, what is the free energy change if 1 mole of Na* is transported across a membrane from a region where the concentration is 1 µM to a region where it is 100 mM? (Assume T = 37 °C) (a) In the absence of a membrane potential. (b) When the transport is opposed by a membrane potential of 70 mV. (c) In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplamic concentrations: ATP = 4.60 mM, P; = 5.10 mM, ADP = 310 µM?
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