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Denise, one of your coworkers at a biotech company is leading a project to improve the stability and lifetime of enzymes used in a continuous reactor. Her team has immobilized the enzyme in porous spheres with a 5 mm diameter and placed them in a packed column to allow the substrate solution to flow through and react to form

Denise, one of your coworkers at a biotech company is leading a project to improve the stability and lifetime of enzymes used in a continuous reactor. Her team has immobilized the enzyme in porous spheres with a 5 mm diameter and placed them in a packed column to allow the substrate solution to flow through and react to form

Introduction to Chemical Engineering Thermodynamics
Introduction to Chemical Engineering Thermodynamics
8th Edition
ISBN:9781259696527
Author:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Publisher:J.M. Smith Termodinamica en ingenieria quimica, Hendrick C Van Ness, Michael Abbott, Mark Swihart
Chapter1: Introduction
Section: Chapter Questions
Problem 1.1P
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5. Denise, one of your coworkers at a biotech company is leading a project to improve the stability and lifetime of enzymes used in a continuous reactor. Her team has immobilized the enzyme in porous spheres with a 5 mm diameter and placed them in a packed column to allow the substrate solution to flow through and react to form product. Denise claims that the immobilized enzymes will save the company $50,000 per month by reducing the amount of new enzyme that must be bought, since this enzyme degrades in solution with a half-life of 10 days when free in solution. Her column packed with immobilized enzyme has a half-life of 30 days. The half-life is measured by the time before the reaction velocity is reduced to half of it's initial value with fresh enzyme. The free solution enzyme and packed column run under identical conditions of pH, temperature and solution composition. Is Denise's reasoning right? What additional information would you need to either confirm or refute Denise's claim?
Transcribed Image Text:5. Denise, one of your coworkers at a biotech company is leading a project to improve the stability and lifetime of enzymes used in a continuous reactor. Her team has immobilized the enzyme in porous spheres with a 5 mm diameter and placed them in a packed column to allow the substrate solution to flow through and react to form product. Denise claims that the immobilized enzymes will save the company $50,000 per month by reducing the amount of new enzyme that must be bought, since this enzyme degrades in solution with a half-life of 10 days when free in solution. Her column packed with immobilized enzyme has a half-life of 30 days. The half-life is measured by the time before the reaction velocity is reduced to half of it's initial value with fresh enzyme. The free solution enzyme and packed column run under identical conditions of pH, temperature and solution composition. Is Denise's reasoning right? What additional information would you need to either confirm or refute Denise's claim?
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