In most enzymes, the required active site amino acids consists of only a few residues. Why is the rest of the protein necessary for full enzyme function? To bind to the membrane through hydrophobic residues. To interact with other proteins so that the enzyme can be imported into the endoplasmic reticulum where enzymes are the most active. To provide the correct tertiary structure for the substrate binding site and for proper orientation of the catalytic residues. To provide protein targeting sequences so that the enzyme can be transported to the mitochondrial matrix where gluconeogenesis takes place.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Transcription for Educational Website:**

**Understanding Enzyme Functionality:**

In most enzymes, the required active site amino acids consist of only a few residues. Why is the rest of the protein necessary for full enzyme function?

- ○ To bind to the membrane through hydrophobic residues.

- ○ To interact with other proteins so that the enzyme can be imported into the endoplasmic reticulum where enzymes are the most active.

- ○ To provide the correct tertiary structure for the substrate binding site and for proper orientation of the catalytic residues.

- ○ To provide protein targeting sequences so that the enzyme can be transported to the mitochondrial matrix where gluconeogenesis takes place.
Transcribed Image Text:**Transcription for Educational Website:** **Understanding Enzyme Functionality:** In most enzymes, the required active site amino acids consist of only a few residues. Why is the rest of the protein necessary for full enzyme function? - ○ To bind to the membrane through hydrophobic residues. - ○ To interact with other proteins so that the enzyme can be imported into the endoplasmic reticulum where enzymes are the most active. - ○ To provide the correct tertiary structure for the substrate binding site and for proper orientation of the catalytic residues. - ○ To provide protein targeting sequences so that the enzyme can be transported to the mitochondrial matrix where gluconeogenesis takes place.
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