In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?   The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual. None of the other answers are correct. The AY allele lacks an upstream merc gene which is required for normal embryonic development. The AY allele contains a null mutation in the A gene, which is required for normal embryonic development. The yellow pigment produced by A allele is required for survival.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In mice, the A allele causes agouti fur, the AY allele causes yellow fur and is dominant to the A allele. The homozygous AY AY genotype is lethal.   Why is the AYAY homozygous condition lethal?
 
The AY allele highly transcribes the merc gene which is lethal in a homozygous AYAY individual.
None of the other answers are correct.
The AY allele lacks an upstream merc gene which is required for normal embryonic development.
The AY allele contains a null mutation in the A gene, which is required for normal embryonic development.
The yellow pigment produced by A allele is required for survival.
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