In dogs (Canis familiaris), there is a hereditary deafness caused by the recessive gene d. A kennel owner has a male dog (Fido, of course) that she wants to use for breeding purposes. She comes to you for genetlc advice. The dog can hear, so you know that his genotype is either DD or Dd. If Fido's genotype were Dd, the owner would not use him for breeding so that the deafness gene will not be passed on. The dog's genotype can be ascertained via a test-cross with a deaf female (dd). Draw Punnett squares or pedigrees to illustrate these two possible crosses. O000 O a. Use fractions or decimals to indicate proportions: In each case, what proportion of the offspring would be expected to be hearing? b. What proportion would be expected to be deaf? c. How could you tell the genotype of the male dog (in parental generation P)? d. Also, using a Punnett square, how would you explain to the kennel owner that two hearing dogs could produce deaf offspring? Indicate to the kennel owner what kind(s) of gametes (ova or sperm) could hearing dogs produce to conceive a deaf puppy
In dogs (Canis familiaris), there is a hereditary deafness caused by the recessive gene d. A kennel owner has a male dog (Fido, of course) that she wants to use for breeding purposes. She comes to you for genetlc advice. The dog can hear, so you know that his genotype is either DD or Dd. If Fido's genotype were Dd, the owner would not use him for breeding so that the deafness gene will not be passed on. The dog's genotype can be ascertained via a test-cross with a deaf female (dd). Draw Punnett squares or pedigrees to illustrate these two possible crosses. O000 O a. Use fractions or decimals to indicate proportions: In each case, what proportion of the offspring would be expected to be hearing? b. What proportion would be expected to be deaf? c. How could you tell the genotype of the male dog (in parental generation P)? d. Also, using a Punnett square, how would you explain to the kennel owner that two hearing dogs could produce deaf offspring? Indicate to the kennel owner what kind(s) of gametes (ova or sperm) could hearing dogs produce to conceive a deaf puppy
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Problem N° 7
Objective: To illustrate the use of test
crosses to establish unknown genotypes.
In dogs (Canis familiaris), there is a hereditary deafness caused by the recessive gene d. A kennel owner has a
male dog (Fido, of course) that she wants to use for breeding purposes. She comes to you for genetlc advice. The
dog can hear, so you know that his genotype is either DD or Dd.
For this problem, you are allowed to use
Punnett squares or pedigrees.
If Fido's genotype were Dd, the owner would not use him for breeding so that the deafness gene will not be
passed on. The dog's genotype can be ascertained via a test-cross with a deaf female (dd). Draw Punnett squares
or pedigrees to illustrate these two possible crosses.
A test cross uses an individual whose
genotype we can be certain of, i.e., a
homozygous recessive for a particular trait.
Such organism is crossed with one whose
genotype we do not know (remember the
homozygous recessive always express the
recessive phenotype). In this case, a dd dog
will be deaf and a hearing dog can be DD or
Dd (i.e., D- represents both homozygous
dominant and heterozygous until the
genotype is determined).
O000
of
The results of a test cross will be either
dd X DD → All Dd (all hearing), the unkonwn
genotype is DD;
a. Use fractions or decimals to indicate proportions: In each case, what proportion of the offspring
would be expected to be hearing?
or
dd X Dd > % Dd + % dd (half hearing,
half deaf), the unknown
genotype is Dd.
b. What proportion would be expected to be deaf?
So, the proportion of hearing dogs will
indicate the unknown genotype.
c. How could you tell the genotype of the male dog (in parental generation P)?
d. Also, using a Punnett square, how would you explain to the kennel owner that two hearing dogs
could produce deaf offspring? Indicate to the kennel owner what kind(s) of gametes (ova or sperm)
could hearing dogs produce to conceive a deaf puppy
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