In cats, a gene on the X chromosome (X-linked) makes the protein amelogenin, which helps direct the formation of tooth enamel. A mutation in an amelogenin allele changes the amino acid sequence of the protein and can cause a condition called amelogenesis imperfecta, leading to defects in a cat’s tooth enamel. In one type of amelogenesis imperfecta in cats, the allele associated with the condition, a, acts in a recessive manner. Its dominant counterpart, A, results in normal levels of amelogenin. Additionally, the dominant allele H at an autosomal locus that regulates the expression of the protein Sonic Hedgehog is responsible for polydactyly (the presence of extra digits on each foot, “double paws”) and the expression of its recessive counterpart h results in the absence of polydactyly (having the 5 digits per front paw, and 4 digits per hind paw). A female cat who has normal teeth and the normal number of toes gives birth to a male kitten with polydactyly and amelogenesis imperfecta. What can you conclude about the genotypes of the male kitten and his two parents? Unknown alleles should be indicated with a “?” 1. The son? 2. The father? 3. The mother?
Hi im having some trouble with this question, if someone could help solve these with an explanation it would be very helpful! In cats, a gene on the X chromosome (X-linked) makes the protein amelogenin, which helps direct the formation of tooth enamel. A mutation in an amelogenin allele changes the amino acid sequence of the protein and can cause a condition called amelogenesis imperfecta, leading to defects in a cat’s tooth enamel. In one type of amelogenesis imperfecta in cats, the allele associated with the condition, a, acts in a recessive manner. Its dominant counterpart, A, results in normal levels of amelogenin. Additionally, the dominant allele H at an autosomal locus that regulates the expression of the protein Sonic Hedgehog is responsible for polydactyly (the presence of extra digits on each foot, “double paws”) and the expression of its recessive counterpart h results in the absence of polydactyly (having the 5 digits per front paw, and 4 digits per hind paw). A female cat who has normal teeth and the normal number of toes gives birth to a male kitten with polydactyly and amelogenesis imperfecta. What can you conclude about the genotypes of the male kitten and his two parents? Unknown alleles should be indicated with a “?”
1. The son?
2. The father?
3. The mother?
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