The top chromosome carries the recessive b allele, and the bottom chromosome carries the dominant B allele. Gene region ъ 5' 3' 3" 5' в A double-strand break occurs within the recessive gene. в A region adjacent to the double- strand break is digested away, which eliminates the recessive b allele. в Strand invasion causes D-loop formation. в Gap repair synthesis uses the strands from the dominant B allele to fill in the region. в The intertwined strands are resolved. в в Both chromosomes carry the B allele. FIGURE 20.5 Gene conversion by gap repair synthesis accord- ing to the double-strand break model. A gene is found in two alleles, des- ignated b and B. A double-strand break occurs in the DNA encoding the b alkele. Both of these DNA strands are digested away, thereby eliminating the b allele. A complementary DNA strand encoding the B allele migrates to this region and provides the template to synthesize a new double-stranded region. Following resolution, both DNA double helices carry the B allele.
The top chromosome carries the recessive b allele, and the bottom chromosome carries the dominant B allele. Gene region ъ 5' 3' 3" 5' в A double-strand break occurs within the recessive gene. в A region adjacent to the double- strand break is digested away, which eliminates the recessive b allele. в Strand invasion causes D-loop formation. в Gap repair synthesis uses the strands from the dominant B allele to fill in the region. в The intertwined strands are resolved. в в Both chromosomes carry the B allele. FIGURE 20.5 Gene conversion by gap repair synthesis accord- ing to the double-strand break model. A gene is found in two alleles, des- ignated b and B. A double-strand break occurs in the DNA encoding the b alkele. Both of these DNA strands are digested away, thereby eliminating the b allele. A complementary DNA strand encoding the B allele migrates to this region and provides the template to synthesize a new double-stranded region. Following resolution, both DNA double helices carry the B allele.
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Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
Question
Explain what happened to the b allele that allowed gene conversion to occur.
Transcribed Image Text:The top chromosome carries the recessive
b allele, and the bottom chromosome
carries the dominant B allele.
Gene region
ъ
5'
3'
3"
5'
в
A double-strand break occurs
within the recessive gene.
в
A region adjacent to the double-
strand break is digested away,
which eliminates the recessive b allele.
в
Strand invasion causes
D-loop formation.
Transcribed Image Text:в
Gap repair synthesis uses the strands
from the dominant B allele to fill in the
region.
в
The intertwined
strands are resolved.
в
в
Both chromosomes carry the B allele.
FIGURE 20.5 Gene conversion by gap repair synthesis accord-
ing to the double-strand break model. A gene is found in two alleles, des-
ignated b and B. A double-strand break occurs in the DNA encoding the
b alkele. Both of these DNA strands are digested away, thereby eliminating
the b allele. A complementary DNA strand encoding the B allele migrates to
this region and provides the template to synthesize a new double-stranded
region. Following resolution, both DNA double helices carry the B allele.
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