Immunology   1) What is the purpose of class I MHC molecules? What cells display these molecules? Where do the antigens they display come from?   a) What is the purpose of class II MHC molecules? What cells display these molecules? Where do the antigens they display come from?   b) What kind of proteins are considered class III MHC molecules? What role in immunity do they play?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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Immunology

 

1) What is the purpose of class I MHC molecules? What cells display these molecules? Where do the antigens they display come from?

 

a) What is the purpose of class II MHC molecules? What cells display these molecules? Where do the antigens they display come from?

 

b) What kind of proteins are considered class III MHC molecules? What role in immunity do they play?

 

c) Which cells are professional APCs? Name the 3 examples of true professional APCs.

 

d) Give an example of a nonprofessional APC. When can these cells function in antigen presentation?

 

e) A process called antigen cross-presentation happens in dendritic cells only. Explain what cross-presentation is.

 

f) Molecules of the CD1 family have been shown to present non-peptide antigens. What types of antigens do they present? Which cell do they present those antigens to?

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