I need help calculating observed allelic frequencies. I'm in a biology lab and we did a classroom experiment where we were each given genotypes and simulated multiple generations by coinflip. This is the end data after multiple generations and we need to extrapolate p & q: AA individuals - 2 Aa individuals - 13 aa individuals - 5 My understanding is that the genotypic frequencies would simply be their %. So AA would be 0.1, Aa would be 0.65, and aa would be 0.25. This should mean that AA = 0.1 = p^2 and aa = 0.25 = q^2. Which should also mean that taking the square root of these numbers would give me p and q.... but they don't add up to 1. Squaring them gives me a p value of ~0.32 and a q value of 0.5. How is this possible? Shouldn't this method work to give me p and q since I know the exact genotypic frequencies? If anyone can clear up why this doesn't work, I would be extremely appreciative. Thank you!
Genetic Variation
Genetic variation refers to the variation in the genome sequences between individual organisms of a species. Individual differences or population differences can both be referred to as genetic variations. It is primarily caused by mutation, but other factors such as genetic drift and sexual reproduction also play a major role.
Quantitative Genetics
Quantitative genetics is the part of genetics that deals with the continuous trait, where the expression of various genes influences the phenotypes. Thus genes are expressed together to produce a trait with continuous variability. This is unlike the classical traits or qualitative traits, where each trait is controlled by the expression of a single or very few genes to produce a discontinuous variation.
I need help calculating observed allelic frequencies. I'm in a biology lab and we did a classroom experiment where we were each given genotypes and simulated multiple generations by coinflip.
This is the end data after multiple generations and we need to extrapolate p & q:
AA individuals - 2
Aa individuals - 13
aa individuals - 5
My understanding is that the genotypic frequencies would simply be their %. So AA would be 0.1, Aa would be 0.65, and aa would be 0.25. This should mean that AA = 0.1 = p^2 and aa = 0.25 = q^2. Which should also mean that taking the square root of these numbers would give me p and q.... but they don't add up to 1. Squaring them gives me a p value of ~0.32 and a q value of 0.5. How is this possible? Shouldn't this method work to give me p and q since I know the exact genotypic frequencies?
If anyone can clear up why this doesn't work, I would be extremely appreciative. Thank you!
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