For each scenario below, choose the options that matches. Write the number in the blank next to the scenario. 1. Co-dominance 2. Complementation 3. Dominant negative 4. Epistasis 5. Expressivity 6. Incomplete dominance 7. Incomplete penetrance 8. Lethality 9. Linkage 10. Maternal effect 11. Mitochondrial inheritance 12. Pleiotropy 13. Sex influenced trait 14. Sex-linked trait 15. Suppression

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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For each scenario below, choose the options that
matches. Write the number in the blank next to the scenario.

1. Co-dominance

2. Complementation

3. Dominant negative

4. Epistasis

5. Expressivity

6. Incomplete dominance

7. Incomplete penetrance

8. Lethality

9. Linkage

10. Maternal effect

11. Mitochondrial inheritance

12. Pleiotropy

13. Sex influenced trait

14. Sex-linked trait

15. Suppression

Li) A cat was born with a dominant mutation in the M gene, which makes a muscle protein, and due to this
mutation, the claw muscles cannot retract. This makes the unfortunate cat more like a dog. This mutation
got passed to the cat's progeny; several generations down, a kitten with the mutant M allele was born with
an additional, new mutation in a different muscle protein that restored the claw-retraction ability.
j) Cats have "radar ears," that can rotate to face the sound source. The ability to rotate requires both the R1
gene, and the R2 gene. So cats that are R1R11212 cannot rotate their ears. Neither are cats that are
r1r1R2R2. But if these cats mate, all of their kittens can rotate their ears. (Hint: this could be an epistasis
question, but it is not.)
_k) A mutant cat was discovered that used oxygen at super high rates. Her metabolism was through the roof!
She had 6 kittens-3 girls and 3 boys. All of them had the same high-metabolism phenotype. These 6 kittens
went on to have their own kittens, all with their own separate mates; all the kittens of the female cats had
the same phenotype, but the kittens of the male cats were all normal.
I) The B1 allele makes blue fur, the B2 makes yellow fur, and cats with B1B2 have green fur because there is a
mixture of blue and yellow pigments in the fur which under the microscope appear as separate dots but to
the naked eye appear green.
m) Cats hiss when they are angry or scared. In order to hiss, they release hot steam from the hissing gland,
which makes the hissing sound. The H gene controls whether the hiss is loud or soft; the enzyme encoded by
the gene results in either high pressure steam (H; loud hiss) or low pressure steam (h; soft hiss.) However,
the W gene controls whether or not water is let into the hiss gland. WW and Ww cats let water in, where it
can become steam, but ww cats don't let water in and as a result, there is no hiss even though the gland
gets hot.
n) The J gene controls how high cats jump; JJ and Jj cats jump higher than jj cats do. The P gene controls how
loudly they purr; PP and Pp cats purr more loudly than pp cats do. In a cross between JjPp cats and jjpp cats,
half of the offspring jumped high and purred loudly, and half jumped low and purred softly. No cats jumped
high but purred softly or jumped low or purred loudly. The J and P genes were mapped to the same
chromosome as each other, but not to the same spot on the chromosome.
o) Ignore what you learned from a previous question about cat claw genes. In this scenario, unborn kittens
whose claws are too sharp pierce the placenta, thus killing the kitten. CC and Cc have normal claws, but cc
kittens have extra sharp claws. In a cross between Cc and Cc cats, all of the kittens' genotypes are either CC
or Cc; none are cc.
Transcribed Image Text:Li) A cat was born with a dominant mutation in the M gene, which makes a muscle protein, and due to this mutation, the claw muscles cannot retract. This makes the unfortunate cat more like a dog. This mutation got passed to the cat's progeny; several generations down, a kitten with the mutant M allele was born with an additional, new mutation in a different muscle protein that restored the claw-retraction ability. j) Cats have "radar ears," that can rotate to face the sound source. The ability to rotate requires both the R1 gene, and the R2 gene. So cats that are R1R11212 cannot rotate their ears. Neither are cats that are r1r1R2R2. But if these cats mate, all of their kittens can rotate their ears. (Hint: this could be an epistasis question, but it is not.) _k) A mutant cat was discovered that used oxygen at super high rates. Her metabolism was through the roof! She had 6 kittens-3 girls and 3 boys. All of them had the same high-metabolism phenotype. These 6 kittens went on to have their own kittens, all with their own separate mates; all the kittens of the female cats had the same phenotype, but the kittens of the male cats were all normal. I) The B1 allele makes blue fur, the B2 makes yellow fur, and cats with B1B2 have green fur because there is a mixture of blue and yellow pigments in the fur which under the microscope appear as separate dots but to the naked eye appear green. m) Cats hiss when they are angry or scared. In order to hiss, they release hot steam from the hissing gland, which makes the hissing sound. The H gene controls whether the hiss is loud or soft; the enzyme encoded by the gene results in either high pressure steam (H; loud hiss) or low pressure steam (h; soft hiss.) However, the W gene controls whether or not water is let into the hiss gland. WW and Ww cats let water in, where it can become steam, but ww cats don't let water in and as a result, there is no hiss even though the gland gets hot. n) The J gene controls how high cats jump; JJ and Jj cats jump higher than jj cats do. The P gene controls how loudly they purr; PP and Pp cats purr more loudly than pp cats do. In a cross between JjPp cats and jjpp cats, half of the offspring jumped high and purred loudly, and half jumped low and purred softly. No cats jumped high but purred softly or jumped low or purred loudly. The J and P genes were mapped to the same chromosome as each other, but not to the same spot on the chromosome. o) Ignore what you learned from a previous question about cat claw genes. In this scenario, unborn kittens whose claws are too sharp pierce the placenta, thus killing the kitten. CC and Cc have normal claws, but cc kittens have extra sharp claws. In a cross between Cc and Cc cats, all of the kittens' genotypes are either CC or Cc; none are cc.
a) Cat researchers studying the T gene found that TT cats hold their tails
13. Sex influenced trait
vertically, but tt cats let their tails droop. They were surprised to see that Tt cats
14. Sex-linked trait
also let their tails droop.
15. Suppression
b) A group of cat researchers studying tooth sharpness found a gene that controls
it; they called it the S gene. SS or Ss gave sharp teeth; ss teeth were dull.
Studying claw sharpness, another group of cat researchers found a gene that controls it; they called it the C
gene. CC or Cc cats had sharp claws; cc cats had dull claws. When the cat genome was mapped, it turned out
that the C and S genes mapped the same exact spot, and it was confirmed that they were in fact the exact
same gene. So cc aka ss cats have dull teeth and dull claws.
c) A female cat has a single mutation in a certain gene, and she is totally normal. However, a male cat has the
very same single mutation in the same gene, and he has a mutant phenotype.
d) The M gene in cats determines how much they like to hunt mice. MM and Mm cats really like to hunt mice;
mm cats would rather just hang out on someone's laptop computer. Two Mm cats mated and had a kitten.
DNA analysis showed that this kitten was mm, and yet, he liked to hunt mice. The mom cat also had some
internal abnormalities, allowing her stomach to sort of connect with her uterus. Researchers hypothesized
that while inside his mom's uterus, this mm kitten saw the pieces of mice his mom ate as the pieces passed
by, and because he was bored, he learned to chase mice pieces before birth; thus he came out chasing mice
in spite of his genotype.
Le) Most cats have pads on their feet. The functional P gene produce the enzyme necessary to produce the
pads. pp cats therefore lack pads, so they walk loudly. In a cross between Pp and Pp cats, only 50% of the
kittens have pads on their feet.
_f) The B gene in cats controls how often they bathe. BB cats bathe three times/hour, Bb cats bathe once per
hour, and bb cats bathe once every three hours.
g) The dominant W allele promotes whisker formation; ww and Ww cats have whiskers. ww cats lack
whiskers. But WW cats have anywhere between 5 and 50 whiskers. (Ww cats can also have anywhere
between 5 and 50 whiskers).
h) As we all know, only male cats have whiskers. Because facial hair is, like, a guy thing. As we learned in the
problem above, the W allele is responsible for whisker formation. A WW male cat and a WW female cat
have 20 kittens but only about half of them have whiskers. (Hint: the answer does NOT involve penetrance.)
Transcribed Image Text:a) Cat researchers studying the T gene found that TT cats hold their tails 13. Sex influenced trait vertically, but tt cats let their tails droop. They were surprised to see that Tt cats 14. Sex-linked trait also let their tails droop. 15. Suppression b) A group of cat researchers studying tooth sharpness found a gene that controls it; they called it the S gene. SS or Ss gave sharp teeth; ss teeth were dull. Studying claw sharpness, another group of cat researchers found a gene that controls it; they called it the C gene. CC or Cc cats had sharp claws; cc cats had dull claws. When the cat genome was mapped, it turned out that the C and S genes mapped the same exact spot, and it was confirmed that they were in fact the exact same gene. So cc aka ss cats have dull teeth and dull claws. c) A female cat has a single mutation in a certain gene, and she is totally normal. However, a male cat has the very same single mutation in the same gene, and he has a mutant phenotype. d) The M gene in cats determines how much they like to hunt mice. MM and Mm cats really like to hunt mice; mm cats would rather just hang out on someone's laptop computer. Two Mm cats mated and had a kitten. DNA analysis showed that this kitten was mm, and yet, he liked to hunt mice. The mom cat also had some internal abnormalities, allowing her stomach to sort of connect with her uterus. Researchers hypothesized that while inside his mom's uterus, this mm kitten saw the pieces of mice his mom ate as the pieces passed by, and because he was bored, he learned to chase mice pieces before birth; thus he came out chasing mice in spite of his genotype. Le) Most cats have pads on their feet. The functional P gene produce the enzyme necessary to produce the pads. pp cats therefore lack pads, so they walk loudly. In a cross between Pp and Pp cats, only 50% of the kittens have pads on their feet. _f) The B gene in cats controls how often they bathe. BB cats bathe three times/hour, Bb cats bathe once per hour, and bb cats bathe once every three hours. g) The dominant W allele promotes whisker formation; ww and Ww cats have whiskers. ww cats lack whiskers. But WW cats have anywhere between 5 and 50 whiskers. (Ww cats can also have anywhere between 5 and 50 whiskers). h) As we all know, only male cats have whiskers. Because facial hair is, like, a guy thing. As we learned in the problem above, the W allele is responsible for whisker formation. A WW male cat and a WW female cat have 20 kittens but only about half of them have whiskers. (Hint: the answer does NOT involve penetrance.)
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